About this trial
Laparoscopic surgery is widely used now. These benefits included many items, e.g. reducing post-operative pain, cosmetic the result was improved, and the patient also had more satisfaction for the patient and reduced hospital stay. This surgery involved insufflation of gas into the peritoneal cavity, producing pneumoperitoneum, and causing an increase in intra-abdominal pressure. The raised intraabdominal pressure of the pneumoperitoneum, the patient's position alteration, and the absorption of carbon dioxide into the abdomen have a direct effect on causing a change in physiology, especially in the cardiovascular and respiratory systems. These effects, as well as a direct effect of gas insufflation, may have significant effects on the patient especially if the patient has a comorbidity or is elderly.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
elective abdominal surgery
a healthy, fit person
use of general anesthetics
use of pneumoperitoneum and CO2 insufflation
Disqualifiers
emergency condition
patient with cardiovascular disease
Trial design
Single group
Treatments tested in this trial
general anesthesia drug (like Propofol, esmeron, and ketamin, .effects of pneumoperitoneum
Procedure/Surgerythis research will involve the selection of elective cases with ASA class I or II and assessment of patients with respiratory cardiovascular parameters and hematology perioperative
Treatment groups
Trial outcomes
Primary outcomes
blood pressure.
blood pressure in mmHg, pulse rate in beat per minute
AST and ALT liver enzymes were measured, by blood samples taken intravenously in the perioperative period
in unit/liter
blood sugar, should measured and assessed with different groups
blood sugar in mg/dl
end-tidal Co2, measured and compared statistically with other parameter
End-tidal Co2 in CMH2O
Secondary outcomes
measurement of body weight
in Kg
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Mohammed Abdulhameed
Lead sponsor
Tunis University
Sponsor institution
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