About this trial
The aim of this study is to investigate whether there are differences in muscle activation of the first dorsal interosseous (FDI) and the abductor pollicis longus (APL) between individuals with and without thumb trapeziopometacarpal joint osteoarthritis (OA TMC) during the performance of activities of daily living (ADL).
The FDI muscle has been identified as a key stabilizer of the thumb TMC joint. However, scientific literature lacks information regarding the activation of the FDI and the APL during ADL, particularly in comparison with healthy individuals. OA TMC can lead to pain, reduced thumb strength, impaired hand function, and difficulty performing ADL. Determining whether differences in muscle activation patterns exist between individuals with and without OA TMC is crucial for understanding how this condition affects hand function and for guiding more specific and effective rehabilitation strategies.
Participants will perform six standardized functional tasks simulating everyday activities: turning a key to open, turning a key to close, picking up a coin, writing, squeezing a tube of toothpaste, and holding a glass of water. Muscle activity will be recorded using surface electromyography (sEMG) during all tasks.
Adults aged 30 years and older, both men and women, with thumb CMC osteoarthritis and healthy controls without osteoarthritis will be invited to participate.
Researchers will measure the activation patterns of the FDI and APL muscles during the ADL, with the aim of identifying differences between both groups and providing evidence to guide the rehabilitation of patients with thumb base osteoarthritis.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Clinical diagnosis of thumb TMC osteoarthritis.
Healthy group:Participants with no history of musculoskeletal or neurological disorders affecting the dominant hand were included.
Disqualifiers
Presence of numbness, tingling, or other sensory disturbances
Upper limb entrapment neuropathy or cervical radiculopathy
History of neuromuscular disease, polyneuropathy, or plexopathy
Systemic diseases such as diabetes, hypothyroidism, or chronic liver or kidney disease
Trial population
The study population will include adults aged 18 years and older, both men and women, divided into two groups. The first group will consist of individuals with a clinical diagnosis of thumb trapeziometacarpal osteoarthritis, and the second group will consist of healthy controls without musculoskeletal or neurological disorders affecting the hand.
Trial design
Case-control
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Surface electromyographic amplitude of the First Dorsal Interosseous muscle.
Mean surface electromyographic amplitude of the First Dorsal Interosseous muscle recorded during each of the 6 activities of daily living
Surface electromyographic amplitude of the Abductor Pollicis Longus muscle
Mean surface electromyographic amplitude of the Abductor Pollicis Longus muscle recorded during each of the 6 activities of daily living.
Sponsors and contacts
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