Thumb Muscle Activation During Different Activities of Daily Living in Thumb Base Osteoarthritis and Healthy Controls

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Malaga

About this trial

The aim of this study is to investigate whether there are differences in muscle activation of the first dorsal interosseous (FDI) and the abductor pollicis longus (APL) between individuals with and without thumb trapeziopometacarpal joint osteoarthritis (OA TMC) during the performance of activities of daily living (ADL).

The FDI muscle has been identified as a key stabilizer of the thumb TMC joint. However, scientific literature lacks information regarding the activation of the FDI and the APL during ADL, particularly in comparison with healthy individuals. OA TMC can lead to pain, reduced thumb strength, impaired hand function, and difficulty performing ADL. Determining whether differences in muscle activation patterns exist between individuals with and without OA TMC is crucial for understanding how this condition affects hand function and for guiding more specific and effective rehabilitation strategies.

Participants will perform six standardized functional tasks simulating everyday activities: turning a key to open, turning a key to close, picking up a coin, writing, squeezing a tube of toothpaste, and holding a glass of water. Muscle activity will be recorded using surface electromyography (sEMG) during all tasks.

Adults aged 30 years and older, both men and women, with thumb CMC osteoarthritis and healthy controls without osteoarthritis will be invited to participate.

Researchers will measure the activation patterns of the FDI and APL muscles during the ADL, with the aim of identifying differences between both groups and providing evidence to guide the rehabilitation of patients with thumb base osteoarthritis.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Clinical diagnosis of thumb TMC osteoarthritis.

Healthy group:Participants with no history of musculoskeletal or neurological disorders affecting the dominant hand were included.

Disqualifiers

Presence of numbness, tingling, or other sensory disturbances

Upper limb entrapment neuropathy or cervical radiculopathy

History of neuromuscular disease, polyneuropathy, or plexopathy

Systemic diseases such as diabetes, hypothyroidism, or chronic liver or kidney disease

Trial population

The study population will include adults aged 18 years and older, both men and women, divided into two groups. The first group will consist of individuals with a clinical diagnosis of thumb trapeziometacarpal osteoarthritis, and the second group will consist of healthy controls without musculoskeletal or neurological disorders affecting the hand.

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

60 Participants
are grouped into 2 trial groups
Group A: OA GROUP
Group B: HEALTHY GROUP

Trial outcomes

Primary outcomes

1

Surface electromyographic amplitude of the First Dorsal Interosseous muscle.

Mean surface electromyographic amplitude of the First Dorsal Interosseous muscle recorded during each of the 6 activities of daily living

Time frame
Day 1
2

Surface electromyographic amplitude of the Abductor Pollicis Longus muscle

Mean surface electromyographic amplitude of the Abductor Pollicis Longus muscle recorded during each of the 6 activities of daily living.

Time frame
Day 1

Secondary outcomes

Other outcomes

Sponsors and contacts

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