Health TrialsbyHealthPanel

Thymoquinone Around Immediate Implant

ConditionsImmediate Dental Implant PlacementJumping GapPrimary Stability of the Implants
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-55
Sponsorshaimaa hamdy

About this trial

use of Thymoquinone hydrogel with bone graft in comparison to bone graft only around immediate implant-this hydrogel fill the jumping zone in comparison to using hydrogel bone graft only to increase primary stability and enhance osseointegration

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

1- Patients ages more than 18 years old, Participants were chosen according to specific eligibility criteria, requiring them to be healthy individuals classified as ASA I by the American Society of Anesthesiologists.

Disqualifiers

Pathologies or drugs that alter tissue integration with dental implants. 2- Head and neck radiation therapy. 3- Renal disease, bleeding disorders and anticoagulant therapy. 4- Pregnant females. 5- Patients with severe para-functional habits and unfavorable occlusion 6- Smokers. 7- Malaligned teeth and teeth with acute periapical pathosis.

Trial design

Design model

Parallel

Treatments tested in this trial

  • group 1 xenograft hydrogel

    Procedure/Surgery

    22 implants will inserted immediately after teeth extraction with xenograft.

  • immediat implant placement wit TQ and bone graft hydrogel placement around implant

    Procedure/Surgery

    22 implants will inserted immediately after teeth extraction, combined xenograft and TQ gel.

Treatment groups

44 Participants
are divided into 2 treatment groups
Group A: surgical implants will inserted immediately after teeth extraction with xenograft.Placebo comparator 1 intervention
Group B: study groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

primary stability

Evaluate the primary stability by osstell pre- and post-3-month during abutment placement, this meaure from 1-99 ISQ

Time frame
0, 3 months

Secondary outcomes

1

secondary outcomes

evaluate amount of bone gain around implant measured by CBCT this measured by mm on CBCT

Time frame
baseline, 3 months, and 6 months
2

secondary outcome

clinical periodontal parameters (CAL, PD, and BOP), which were measured using periodontal probe by mm

Time frame
3 months and 6 months

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

shaimaa hamdy

Lead sponsor

Minia University

Sponsor institution

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: