Timing of Recruitment Maneuver in Robotic Prostate Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18+
SponsorAnkara University

About this trial

Robotic prostate surgery is commonly performed under general anesthesia with carbon dioxide pneumoperitoneum and steep Trendelenburg positioning. These conditions may reduce lung volumes, impair respiratory mechanics, and increase the risk of atelectasis and postoperative pulmonary complications. Recruitment maneuvers combined with individualized positive end-expiratory pressure may improve intraoperative oxygenation and lung compliance; however, the optimal timing of recruitment maneuver application in robotic prostate surgery remains unclear.

This prospective randomized study aims to compare the effects of recruitment maneuver timing on postoperative pulmonary complications in adult patients undergoing elective robotic prostate surgery. Participants will be randomized into two groups. In the Supine Recruitment Group, the recruitment maneuver will be performed before carbon dioxide insufflation while the patient is in the supine position, followed by individualized PEEP determination. In the Trendelenburg Recruitment Group, the recruitment maneuver will be performed after pneumoperitoneum and Trendelenburg positioning, followed by individualized PEEP determination. Patients will be evaluated for postoperative pulmonary complications up to postoperative 72 hours or until discharge, whichever occurs first.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients scheduled for elective robotic prostate surgery

Age 18 years or older

Body mass index between 18 and 35 kg/m²

No cognitive impairment

Disqualifiers

Age younger than 18 years

Emergency surgery

Preoperative oxygen requirement

Cognitive impairment

Trial design

Design model

Parallel

Treatments tested in this trial

  • Recruitment maneuver after insufflation and Trendelenburg positioning

    Procedure/Surgery

    A lung recruitment maneuver will be applied after pneumoperitoneum and Trendelenburg positioning, followed by individualized PEEP determination using decremental PEEP titration.

  • Recruitment maneuver in the supine position

    Procedure/Surgery

    The recruitment maneuver will be performed while the patient is in the supine position, before pneumoperitoneum insufflation and Trendelenburg positioning during robotic prostate surgery. The maneuver will be applied according to the predefined intraoperative ventilation protocol to improve alveolar recruitment and reduce postoperative pulmonary complications.

Treatment groups

86 Participants
are divided into 2 treatment groups
Group A: Supine Recruitment GroupExperimental treatment 1 intervention
Group B: Trendelenburg Recruitment GroupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Incidence of postoperative pulmonary complications

Postoperative pulmonary complications will be evaluated after surgery, including clinically relevant pulmonary events such as atelectasis, hypoxemia, respiratory infection, bronchospasm, aspiration pneumonitis, respiratory failure, need for noninvasive or invasive ventilatory support, or other predefined pulmonary complications according to the study protocol.

Time frame
From the end of surgery to postoperative 72 hours or until hospital discharge, whichever occurs first.

Secondary outcomes

1

Length of hospital stay

Duration of hospital stay will be recorded in days from the day of surgery to hospital discharge.

Time frame
From the day of surgery to hospital discharge, assessed up to 30 days.

Other outcomes

1

Intraoperative respiratory system compliance and oxygenation

Respiratory system compliance will be recorded during mechanical ventilation at predefined intraoperative time points.

Time frame
Intraoperative period

Sponsors and contacts

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