About this trial
Robotic prostate surgery is commonly performed under general anesthesia with carbon dioxide pneumoperitoneum and steep Trendelenburg positioning. These conditions may reduce lung volumes, impair respiratory mechanics, and increase the risk of atelectasis and postoperative pulmonary complications. Recruitment maneuvers combined with individualized positive end-expiratory pressure may improve intraoperative oxygenation and lung compliance; however, the optimal timing of recruitment maneuver application in robotic prostate surgery remains unclear.
This prospective randomized study aims to compare the effects of recruitment maneuver timing on postoperative pulmonary complications in adult patients undergoing elective robotic prostate surgery. Participants will be randomized into two groups. In the Supine Recruitment Group, the recruitment maneuver will be performed before carbon dioxide insufflation while the patient is in the supine position, followed by individualized PEEP determination. In the Trendelenburg Recruitment Group, the recruitment maneuver will be performed after pneumoperitoneum and Trendelenburg positioning, followed by individualized PEEP determination. Patients will be evaluated for postoperative pulmonary complications up to postoperative 72 hours or until discharge, whichever occurs first.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients scheduled for elective robotic prostate surgery
Age 18 years or older
Body mass index between 18 and 35 kg/m²
No cognitive impairment
Disqualifiers
Age younger than 18 years
Emergency surgery
Preoperative oxygen requirement
Cognitive impairment
Trial design
Parallel
Treatments tested in this trial
Recruitment maneuver after insufflation and Trendelenburg positioning
Procedure/SurgeryA lung recruitment maneuver will be applied after pneumoperitoneum and Trendelenburg positioning, followed by individualized PEEP determination using decremental PEEP titration.
Recruitment maneuver in the supine position
Procedure/SurgeryThe recruitment maneuver will be performed while the patient is in the supine position, before pneumoperitoneum insufflation and Trendelenburg positioning during robotic prostate surgery. The maneuver will be applied according to the predefined intraoperative ventilation protocol to improve alveolar recruitment and reduce postoperative pulmonary complications.
Treatment groups
Trial outcomes
Primary outcomes
Incidence of postoperative pulmonary complications
Postoperative pulmonary complications will be evaluated after surgery, including clinically relevant pulmonary events such as atelectasis, hypoxemia, respiratory infection, bronchospasm, aspiration pneumonitis, respiratory failure, need for noninvasive or invasive ventilatory support, or other predefined pulmonary complications according to the study protocol.
Secondary outcomes
Length of hospital stay
Duration of hospital stay will be recorded in days from the day of surgery to hospital discharge.
Other outcomes
Intraoperative respiratory system compliance and oxygenation
Respiratory system compliance will be recorded during mechanical ventilation at predefined intraoperative time points.
Sponsors and contacts
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