Tissue Collection for Drug Screening and Bioanalysis
ConditionCentral Nervous System Tumor
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorWeill Medical College of Cornell University
About this trial
The purpose of this study is to improve upon the knowledge currently available about central nervous system (CNS) tumors. We will study the different characteristics of these tumors using tissue samples collected during surgery and post-autopsy. The aim is to create tumor cell lines and models to test how they respond to different drugs. This research will help improve treatment options and identify new targets for therapy.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Subject has presented with a suspected/confirmed neoplastic CNS lesion and is undergoing a neurosurgical procedure in which CNS tissue and/or tumors associated with this tissue will be removed.
There must be tissue available in excess of that required by neuropathology for diagnostic purposes.
Subject of all ages included.
Subjects who are pregnant can be included.
Disqualifiers
None
Trial population
Patients with a central nervous system tumors. Parents of patients with CNS tumors.
Trial design
Design model
Case-only
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
500 Participants
are grouped into 4 trial groupsGroup A: Cohort 1: Tumor patients undergoing neurosurgery
Group B: Parents of tumor patients
Group C: Cohort 2: Non-Tumor patients undergoing neurosurgery
Group D: Cohort 3: Autopsy tumor tissue donation
Trial outcomes
Primary outcomes
1
Evaluating and characterizing the genetic, immunohistochemical, cellular, and molecular profiles of pediatric neoplastic lesions
To develop patient-derived tissue cell lines and xenografts
Time frame
Through study completion, average 1-3 yearsSponsors and contacts
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Source ClinicalTrials.gov