Topical Intranasal Anesthetic Block for Reducing the Pain of Botulinum Toxin Injections for Chronic Migraine
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAssociation of Migraine Disorders
About this trial
People find the injections used in onabotulinumtoxinA (Botox®) uncomfortable. This study will test whether putting a small piece of cotton soaked with 4% lidocaine (a numbing medicine) inside the front of each nostril for 5 minutes before the injections reduces injection pain compared with cotton soaked in saline (salt water).
Eligibility criteria
Qualifiers
Aged ≥18 years
Any gender
Able to provide informed consent
Meets clinical criteria for onabotulinumtoxinA for chronic migraine (minimum of 2 days of disability per month due to facial or headache pain, or 8 headache days per month, or more than 15 headaches per month)
Disqualifiers
Aged < 18 years
Trigeminal neuralgia, cluster headache, or other primary headache disorders as dominant diagnosis
Not able to provide informed consent
Known allergy/hypersensitivity to lidocaine or amide anesthetics
Trial design
Treatments tested in this trial
- onabotulinumtoxinA prophylaxis with Lidocaine
- OnabotulinumtoxinA prophylaxis with Saline
Treatment groups
18 Participants
are divided into 2 treatment groupsSponsors and collaborators
Association of Migraine Disorders
Lead sponsor
University Otolaryngology
Collaborator
Source ClinicalTrials.gov