Because Propofol is the primary "anesthetic agent," and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.
Pediatric patients <10 years of age
Undergoing elective or emergency surgery with planned airway instrumentation with an endotracheal tube (ETT)
Patients having general anesthesia with a planned SIIVA or TIVA technique
Patients with an end tidal agent concentration of Sevoflurane<0.1% at the time of emergence and extubation
History of home oxygen use or ventilator dependence
Patients with cyanotic congenital heart disease
Patients undergoing anesthesia for imaging procedures alone
Patients intended to be managed with supraglottic airway
All study participants must be \< 10 years of age and undergoing general anesthesia and surgery with an endotracheal tube and using a SIIVA or TIVA approach
Cohort
Prospective
Total intravenous anesthesia (TIVA)
Other interventionTIVA anesthetic -no inhalational gases for surgery
Sevoflurane initiated intravenous anesthesia (SIIVA)
Other interventionSIIVA - sevoflurane anesthetic gases for surgery
Extubation success rate
quality of extubation will be assess using a standard rubric for all extubation
Rate of extubation that requiring intervention
desaturation, laryngospasm, airway obstruction or other issues
Number of Subjects that met specific extubation criteria
Assess the presence of specific extubation criteria met during the extubation
Click on the lead sponsor to view all of their trials.
