TPVB or SPSIPB in Pain Management After VATS

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorKoç University

About this trial

The goal of this clinical trial is to compare the analgesic efficacy of thoracal paravertebral block (TPVB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing video-assisted thoracoscopic surgery (VATS). The main questions it aims to answer are:

How will the total perioperative opioid consumption of the patients receiving two different blocks change? How will TPVB and SPSIPB effect the patients' numeric rating scores for pain in the postoperative 24-hour period? How will TPVB and SPSIPB effect the incidence of opioid related side effects?

Participants will be divided in two groups:

TPVB group will receive a TPVB before the surgery. SPSIPB group will receive a SPSIPB nerve block before the surgery. Researchers will compare the results between the groups to see the postoperative effects concerning opioid consumption as well as the pain scores, respiratory parameters and opioid associated side effects.

The hypothesis of this study is that participants receiving SPSIPB for VATS will have a less total opioid consumption 24 hours postoperatively.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients between the age of 18-80 undergoing video-assisted thoracoscopic surgery

Disqualifiers

Allergy to local anaesthetics Chronic opioid use history Patients with psychiatric disorders Patients who are not open to communication Patients with chronic organ failure Patients that do not give consent Patients that need emergency surgery within the first 24 hours of the initial surgery

Trial design

Design model

Parallel

Treatments tested in this trial

  • Serratus Posterior Superior Intercostal Plane Block

    Procedure/Surgery

    Before the induction of general anesthesia, under aseptic conditions, serratus posterior superior intercostal plane block will be performed with a single dose of 30 ml of %0,25 bupivacaine with ultrasound guidance, by the senior anaesthesiologist.

  • Paravertebral Block

    Procedure/Surgery

    Before the induction of general anesthesia, under aseptic conditions, paravertebral block will be performed with a single dose of 30 ml of %0,25 bupivacaine with ultrasound guidance, by the senior anaesthesiologist.

Treatment groups

44 Participants
are divided into 2 treatment groups
Group A: Group SExperimental treatment 1 intervention
Group B: Group PActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Total opioid consumption

all consumed opioids will be converted in morphine equivalents and then added to reach the total dosage

Time frame
24 hours post-surgery

Secondary outcomes

1

Numeric rating scale scores for pain

the scale between 0: no pain and 10:highes pain answered by the participants

Time frame
24 hours post-surgery
2

Opioid related side effects

Nausea, vomiting, pruritis, respiratory depression assessed by yes/no questions

Time frame
24 hours post-surgery

Other outcomes

Sponsors and contacts

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