About this trial
This research is being done to assess the impact of a supervised and structured strength and conditioning program on cardiac remodeling in participants with prostate cancer undergoing treatment with external beam radiation therapy and at least 6 months of Gonadotropin-releasing hormone (GnRH) therapy.
Eligibility criteria
Qualifiers
Have histologically or cytologically confirmed adenocarcinoma of the prostate
Have not received GnRH agonist or antagonist within the last 12 months
Planned for initiation of a GnRH agonist or antagonist or bilateral orchiectomy with an intended treatment duration of ≥ 6 months
Planned for initiation of radiation therapy to the prostate.
Disqualifiers
Has a known medical condition that makes the subject unable to participate in exercise testing (e.g. unrevascularized coronary artery disease, moderate/severe osteoarthritis, prior stroke, or other conditions)
Receiving or planned to receive other cancer therapy not included in Eligibility Criterion 3.1.3 (other than an antiandrogen during the first month of therapy)
The following populations will not be considered for inclusion on this trial.
Trial design
Treatments tested in this trial
- Exercise