Trans-cranial Direct Current Stimulation on Alcohol Craving
ConditionAlcohol Dependence
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-65
SponsorTaipei City Hospital
About this trial
The goal of thisclinical trial is to investigate the efficacy of trans cranial direct current stimulation (tDCS) for alcohol craving in individuals with alcohol dependence. The main question it aims to answer is whether 10 sessions of tDCS can reduce craving for alcohol.
Participants will be randomized into active group and sham group. Researchers will compare the severity of craving in these groups.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Be between 20-65 years of age
have sufficient cognitive function to understand the study and complete the informed consent process
Be diagnosed with alcohol dependence as defined by DSM-IV through a structured interview (Mini-International Neuropsychiatric Interview, M.I.N.I.)
Disqualifiers
Intellectual disabilities
bipolar disorder
Psychosis (schizophrenia)
Major physical illness (brain hemorrhage, brain tumor, myocardial infarction, epilepsy or history of seizures)
Trial design
Design model
Parallel
Treatments tested in this trial
transCranial direct current stimulation
DeviceThe intervention consisted of 20 daily 20-min sessions of bilateral prefrontal tDCS
sham stimulation
DeviceThe sham group consisted of 10 daily 20-min sessions of sham stimulation
Treatment groups
60 Participants
are divided into 2 treatment groupsGroup A: Active tDCSExperimental treatment 1 intervention
Group B: Sham tDCSSham comparator 1 intervention
Trial outcomes
Primary outcomes
1
Change in alcohol craving
Measured by visual analog scale, from 0-10
Time frame
Before intervention (week 0) and after intervention (week 2)Secondary outcomes
1
Change in brain-derived neurotrophic factor (BDNF)
Serum level of BDNF
Time frame
Before intervention (week 0) and after intervention (week 2)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov