About this trial
This study will assess the effects of transcranial alternating current stimulation (tACS) on language recovery after stroke as well as healthy language functions.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
18 years of age or older
Fluent in English
No history of neurological or psychiatric disorders
Diagnosed with post-stroke aphasia by referring physician/neuropsychologist
Disqualifiers
Severe cognitive, auditory or visual impairments that would preclude cognitive and language testing
Presence of major untreated or unstable psychiatric disease
A chronic medical condition that is not treated or is unstable
The presence of cardiac stimulators or pacemakers
Trial design
Single group
Treatments tested in this trial
tACS
DeviceActive or Sham tACS will be applied.
Treatment groups
Trial outcomes
Primary outcomes
tACS changes in language performance verbal STM tasks
Improvement on verbal STM performance as determined by increases in span, accuracy or decreases in reaction time is expected with active tACS.
tACS-dependent neurophysiological changes
Concomitant frequency-specific EEG changes in spectral power and phase synchronization are expected.
Secondary outcomes
Individual differences in tACS responsiveness
tACS responsiveness depending on language impairment types, stroke lesion and language lateralization characteristics will be explored.
Sponsors and contacts
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