In the current study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in improving executive function across neuropsychiatric populations known to have deficits in this cognitive domain.
Male and female outpatients 18-65 years of age
A diagnosis of traumatic brain injury, major depressive disorder, bipolar disorder, schizophrenia, attention deficit hyperactivity disorder, borderline personality disorder and substance use disorders meeting the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria.
Contraindication to tDCS: history or epilepsy, metallic implants in the head and neck, brain stimulators, vagus nerve stimulators, shunts, pacemakers, pregnancy.
Active substance dependence (except for tobacco and cannabis).
Pregnant or nursing females.
Inability to participate in testing procedures.
Parallel
Transcranial Direct Current Stimulation
DeviceIn tDCS, electrodes are applied on the scalp to transmit direct current at low current amplitudes.
8
Treatment groupsSee each treatment group below.
Change in N-Back Task
Working Memory Task
Change in Flanker Task
Attention and Inhibitory Control Task
Change in Multi-Source Interference with International Affective Picture System Task
Cognitive Control During Emotional Regulation Task
Change in Delayed Discounting Task
Decision-Making Task
Change in Stop Signal Task
Ability to Inhibit a Response Task
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