About this trial
Non-invasive neuromonitoring tools such as transcranial doppler, optic nerve envelope diameter measurement and quantitative pupillometry are routinely used in acute brain injured patients as part of multimodal neuromonitoring with the aim, among others, of detecting episodes of intracranial hypertension, each method allowing the study of one of the different pathophysiological mechanisms of its impact.
However, at present there is no data in the literature on the value of these non-invasive neuromonitoring tools in the management of patients undergoing controlled intracranial surgery.
The study aims to help the early detection of postoperative neurological deterioration.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Regulated intracranial surgery: scheduled > 48 hours
French-speaking patient
No opposition from the patient or a relative when the patient is unable to consent
Disqualifiers
Chronic subdural haematoma
Isolated cerebral endovascular procedure
Stereotactic biopsy
Scheduled ventriculoperitoneal shunt or isolated ventriculocisternostomy
Trial population
Patients undergoing planned neurosurgery
Trial design
Case-only
Prospective
Treatments tested in this trial
Non-invasive neuromonitoring evaluation (transcranial doppler, optic nerve envelope diameter and quantitative pupillometry)
Other intervention4 days Post-operation follow-up. Data will be gathered before the surgery and at regular times after the surgery until day 4
Treatment groups
Trial outcomes
Primary outcomes
Evolution of non-invasive neuromonitoring measures (using transcranial doppler)
This emasure will be performed bilaterally at the level of the first part of the middle cerebral artery, the values collected will be: * Systolic, mean and diastolic velocities; pulsatility index * Estimation of intracranial pressure
Evolution of non-invasive neuromonitoring measures (optic nerve envelope diameter)
The diameter of the optic nerve envelope will be collected bilaterally using an ultrasound machine
Evolution of non-invasive neuromonitoring measures (quantitative pupillometry)
The values collected will be : \- Size, quantification of the amplitude of variation to light, latency and speed of constriction of the pupil, presence or absence of anisocoria (defined by a difference \>1mm in size between the two pupils)
Sponsors and contacts
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