Transcranial Magnetic Stimulation in Laryngeal Dystonia

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorUniversidade Federal de Pernambuco

About this trial

This randomized clinical trial with a crossover design aims to investigate the effects of neuromodulation through repetitive transcranial magnetic stimulation (rTMS) applied to patients diagnosed with laryngeal dystonia. Participants will undergo three experimental conditions: (1) rTMS alone, (2) rTMS combined with speech-language therapy, and (3) sham rTMS combined with speech-language therapy. The order of the conditions will be randomized. Each phase of the protocol will consist of five consecutive sessions.

Outcomes will include acoustic vocal quality parameters, perceptual-auditory voice assessment, self-ratings of vocal effort, smoothed cepstral peak prominence measures, and global perceived change following the intervention. It is expected that the study will contribute to a better understanding of the effects of the intervention on vocal outcomes, supporting the optimization and standardization of therapeutic protocols for laryngeal dystonia.

Eligibility criteria

Qualifiers

Adults (≥18 years) of any sex with a confirmed diagnosis of laryngeal dystonia

Participants not undergoing botulinum toxin treatment at the time of the intervention

Ability to provide informed consent

Ability to complete all study assessments and intervention procedures

Disqualifiers

Other forms of dystonia

Vocal fold lesions

Vocal fold paralysis

Contraindications to repetitive transcranial magnetic stimulation (rTMS)

Trial design

Treatments tested in this trial

  • Active rTMS
  • Sham rTMS
  • Speech-Language Therapy

Treatment groups

20 Participants
are divided into 3 treatment groups

Locations

This trial has no locations