According to the 3D-CAM scale, evaluate the incidence of Postoperative Delirium within 5 days after surgery in elderly patients receiving taVNS.The results are expected to provide evidence of the safety and efficacy of perioperative prophylactic use of taVNS in the clinical application of improving postoperative brain health in elderly patients, as well as theoretical and practical basis for subsequent studies or clinical applications.
Age≥65 years
Expected operation time≥ 2 hours
Postoperative hospital stay≥ 4 days
Sign the informed consent form
Neurosurgery or cardiac surgery
Emergency surgery within 6 hours of admission
End-stage disease with an expected survival of < 3 months
Preoperative severe cognitive dysfunction affected perioperative cognitive function assessment
Parallel
transauricular auricular vagus nerve stimulation
Devicetransauricular auricular vagus nerve stimulation
Incidence of POD at discharge or within 5 days postoperatively
POD assessment was performed using the 3D-CAM scale estimate. Assessed 2 times daily until postoperative day 5 or hospital discharge
Incidence of delayed cognitive recovery during hospitalization
The MMSE/MoCA scale were used for evaluation
Incidence of neurocognitive dysfunction at 90 days postoperatively
assessed by AMTS scale
Degree of decline in activities of daily living at 90 days postoperatively
use the IADL score
All-cause mortality
Click on the lead sponsor to view all of their trials.
