Transfer of Microorganisms Between Green Areas and Humans
ConditionMicrobial Colonization
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age4+
SponsorUniversiteit Antwerpen
About this trial
The goal of this study is to understand how visiting green areas affects the human microbiome through microbial transfer. Additionally, the project aims to understand which environmental, health and lifestyle factors can influence these microbiome changes. Participants will visit a green area, provide microbiome samples before and after the visit, and complete questionnaires related to environmental, health, lifestyle and demographic factors.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
None
Trial design
Design model
Single group
Treatments tested in this trial
Visiting a green space
Other interventionParticipants are asked to visit a green space for a defined time period
Treatment groups
150 Participants
are divided into 1 treatment groupGroup A: Green space interventionExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Microbiome changes
Microbiome sequencing will be performed to assess changes in microbial community composition of nasal and skin swabs, focusing on abundances and diversity of different microorganisms and their genes
Time frame
Two time points directly before and after the intervention (on 1 day)Secondary outcomes
1
Specific microorganisms within the skin and nasal microbiomes
Specific microorganisms within the participants' microbiomes will be assessed through culturing of swabs and/or quantification via qPCR
Time frame
Two time points directly before and after the intervention (on 1 day)2
Associations between the human microbiome and environment
Human microbiome composition and diversity (as assessed in outcome "Microbiome changes") will be correlated with the green space environment characteristics, such as the environmental (microbiome) biodiversity
Time frame
Two time points directly before and after the intervention (on 1 day)Other outcomes
1
Self-reported lifestyle
Lifestyle will be assessed using a short questionnaire to understand how it might impact the microbiome (as assessed in outcome "Microbiome changes"), reflecting lifestyle-related parameters such as weekly time spent outdoors (in hours) and frequency of exposure to green environments (e.g., once a year)
Time frame
One time point directly before or after the intervention (on 1 day)2
Self-reported health
Self-reported general health will be assessed using a short questionnaire to understand how it might impact the microbiome (as assessed in outcome "Microbiome changes"), reflecting health-related parameters such as a health rating (from very poor to very good)
Time frame
One time point directly before or after the intervention (on 1 day)3
Self-reported demographic information
Demographic information will be assessed using a short questionnaire to understand how it might impact the microbiome (as assessed in outcome "Microbiome changes"), reflecting demographic parameters such as age (in years), gender, and parent-child relationship (having one or more children)
Time frame
One time point directly before or after the intervention (on 1 day)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov