Health TrialsbyHealthPanel

Translational Initiative to Map Epigenetics in Sleep

ConditionBiological Aging
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorElysium Health

About this trial

The primary aim of TIME-ZZZ is to explore the relationship between chronotype, incidence of depression and biological age, and whether individuals working "out-of-phase" with their chronotype are more likely to exhibit signs of depression and accelerated biological aging.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Has taken an INDEX test within the last 3 months

Has registered at least 1 INDEX kit via the Elysium Health website

Able and willing to provide digital consent to the RSCF, and the TIME-ZZZ Research Subject Consent Form

Disqualifiers

Consent to participate not given

Trial population

Healthy adults

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Surveys

    Other intervention

    Group will complete several surveys

Treatment groups

10,000 Participants
are divided into 1 treatment group
Group A: TIME-ZZZ1 intervention

Trial outcomes

Primary outcomes

1

Effect of being "out of phase" with chronotype on biological age

Determine whether individuals working "out-of-phase" with their chronotype (from TIME-ZZZ survey responses) exhibit higher rates of biological aging compared to those working within their chronotype

Time frame
At baseline

Secondary outcomes

1

Effect of Chronotype Alignment and Depression Risk in Relation to Rate of Aging

Determine the effect of chronotype alignment and depression risk (from TIME-ZZZ surveys) on biological rate of aging

Time frame
At baseline
2

Identification of DNA methylation markers associated with chronotype

Identify specific DNA methylation markers associated with chronotype (from TIME-ZZZ surveys) thereby providing potential insights into the epigenetic regulation of sleep-wake patterns

Time frame
At baseline
3

Identification of DNA methylation markers associated with depression

Identify specific DNA methylation markers associated with depression (from TIME-ZZZ surveys) potentially shedding light on the underlying epigenetic mechanisms involved in the development and progression of depressive disorders.

Time frame
At baseline

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Elysium Health

Lead sponsor

University of Oxford

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: