Trauma Exposure and Suicidal Behaviors in Adolescents Aged 11-17 Hospitalized in Child and Adolescent Psychiatry

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age11-17
SponsorUniversity Hospital, Montpellier

About this trial

It is a comparative monocentric study with longitudinal follow-up at 6 months in adolescents aged between 11 years and 17 years inclusive admitted to complete hospitalization either for suicidal behaviors or for other psychiatric causes. The objective is to explore the experiences of hospitalized adolescents regarding hospitalization, as well as their perceptions of the factors involved in their remission and their experience of the traumatic event(s) if they have been exposed.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age between 11 and 17 years inclusive

Admitted for full-time psychiatric hospitalization

Obtaining consent from at least one of the adolescent's legal representatives and the adolescent's personal assent

Disqualifiers

None

Trial design

Design model

Parallel

Treatments tested in this trial

  • Blood samples

    Biological/Vaccine

    A blood test will be carried out during the inclusion visit, on site, with collection of the time of completion, the last food samples and tobacco consumption. A 2.5 mL Paxgene® tube for whole blood RNA and a 5 mL dry tube for serum will be collected.

  • genetic analysis

    Genetic

    If consent for genetic analyses is obtained, a 4.5 mL EDTA tube to collect native DNA will be taken during the blood test

  • Questionnaires and scales

    Other intervention

    * Child Posttraumatic Checklist (CPC) * Life Event Checklist (LEC-5) * Posttraumatic CheckList-5 * K-SADS * Affective Reactivity Index (ARI) * Child Youth Resilience Measure * Adverse Childhood Experiences International Questionnaire (ACE-IQ) * Metacognitions Questionnaire (MCQ-A) * Cognitive Emotion Regulation Questionnaire (CERQ) * Adolescent Dissociative Experience Scale (A-DES) * Behavioral Rating Inventory of Executive Function Self-Report (BRIEF-2)

Treatment groups

120 Participants
are divided into 2 treatment groups
Group A: suicide groupActive comparator 3 interventions
Group B: non-suicidal groupActive comparator 3 interventions

Trial outcomes

Primary outcomes

1

CPC Questionnaire child version

This questionnaire evaluates the symptoms of PTSD and their frequency in children aged 7 to 18 years, following a traumatic event. Completion time is 15-20 minutes and the total score can range from 0 (no symptoms) to 84 (maximum symptoms) for symptom intensity and from 0 (no functional impact) to 24 (maximum functional impact) for functional impairment. The scale will be administered by a clinician (psychologist or psychiatrist for children and adolescents).

Time frame
Baseline

Secondary outcomes

1

CPC questionnaire parents version

This questionnaire evaluates by parents the symptoms of their children in PTSD and their frequency in children aged 7 to 18 years, following a traumatic event. Completion time is 15-20 minutes and the total score can range from 0 (no symptoms) to 84 (maximum symptoms) for symptom intensity and from 0 (no functional impact) to 24 (maximum functional impact) for functional impairment. The scale will be administered by a clinician or self-administered (psychologist or psychiatrist for children and adolescents).

Time frame
Baseline
2

Questionnaire Life Event Checklist (LEC-5)

The Life Event Checklist version of DSM-5 (19) consists of a list of 16 potentially trauma events in reference to criterion 1 of PTSD from DSM-5. It does not generate a total score but allows for a record of trauma events if they have occurred or not.

Time frame
Baseline
3

Schedule for Affective Disorders and Schizophrenia for school-age children (KSADS) full-life version

It is a hetero-administered questionnaire that allows for the screening and diagnosis of psychiatric and neurodevelopmental disorders in children and adolescents.

Time frame
Baseline
4

Post-traumatic Stress Disorder Checklist for DSM-5 (PCL-5)

The PCL-5 (23) is composed of 20 items that correspond to the 20 PTSD criteria detailed in the DSM-5, and contains four subscales corresponding to the four clusters of symptoms in the DSM-5: intrusion phenomena, avoidance, negative alterations of cognition and mood, and increase in hyperactivity and reactivity. The score can range from 0 (no symptoms) to 80 (maximum symptoms). PCL-5 is a self-administered questionnaire that can also be administered with the help of a clinician.

Time frame
Baseline

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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