Treating Contact Lens Discomfort With Varenicline Solution Nasal Spray 0.03mg

ConditionDry Eye
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-99
SponsorOcular Aesthetics, LLC dba Ocular Clinical Trials

About this trial

The objective of this study is to evaluate whether twice-daily use of Tyrvaya improves contact lens comfort in contact lens wearers.

Eligibility criteria

Qualifiers

Adult male and female subjects of any race or ethnicity who are ≥18 years of age.

Best corrected CL visual acuity of 0.3 Logarithm of the Minimum Angle of Resolution (logMAR) or better in both eyes (Snellen equivalent 20/40).

Soft 1-day silicone hydrogel CL wearer (daily disposable only)

Contact Lens Dry Eye Questionnaire (CLDEQ)-8 scores (CLDEQ-8 scores ≥ 12).16

Disqualifiers

Any history of Tyrvaya use within six months of enrollment

Are currently an overnight CL wearer.

Are currently wearing rigid gas permeable CLs, scleral CL, hybrid CLs, or reusable soft CLs.

Have known systemic health conditions that are known to alter tear film physiology (e.g., primary and secondary Sjögren's syndrome).

Trial design

Treatments tested in this trial

  • Tyrvaya

Treatment groups

50 Participants
are divided into 1 treatment group

Sponsors and collaborators