Treatment of Mandibular Bone Cyst by Navigation and Endoscopy
ConditionJaw Cysts
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen University
About this trial
In this study, with the assistance of endoscopic technology and intraoperative navigation technology, the removal and curettage of large odontogenic jaw cyst occurred in the mandible were performed to reduce the rate of postoperative nerve injury. In this study, the investigators compared the efficacy of traditional extraction and curettage with endoscopic navigation assistance in the treatment of giant mandibular bone cysts. In this study, the rate of inferior alveolar nerve injury 1 month after surgery was taken as the main outcome index, and the recurrence rate 1 year after surgery was taken as the secondary outcome index, to explore whether endoscopic combined with intraoperative navigation-assisted treatment of giant mandibular bone cyst could achieve lower postoperative nerve injury rate and postoperative recurrence rate.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
They are between 18 and 75 years old
Imaging and puncture pathology showed odontogenic cystic lesion of the mandible
Cystic lesions greater than or equal to 2cm in diameter and spread to the inferior alveolar nerve
New or recurrent cyst lesions, or odontogenic cystic lesions that are still greater than or equal to 2cm after other treatment such as fenestration and affecting the lower alveolar nerve
Disqualifiers
The patient has severe systemic disease or pregnancy, and is judged to be unable to tolerate the course of this clinical study and cannot tolerate general anesthesia after evaluation by the research team and multidisciplinary consultation
Inability to complete the entire clinical research process due to personal, social, and economic reasons
Patients with psychiatric disorders or inability to perceive and communicate normally, such as schizophrenia, claustrophobia, etc., are unable to complete the examination and cooperate in the entire clinical research process
Trial design
Design model
Single group
Treatments tested in this trial
Navigation and endoscopy
Procedure/SurgeryThe model was reconstructed using patient CT data, and intraoperative surgery was performed using endoscopy and navigation.
Treatment groups
122 Participants
are divided into 1 treatment groupGroup A: Navigation and endoscopy GroupExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Rate of inferior alveolar nerve injury at one month postoperatively
Rate of inferior alveolar nerve injury at one month postoperatively
Time frame
one monthSecondary outcomes
1
Recurrence rate one year after surgery
Recurrence rate one year after surgery
Time frame
one yearSponsors and contacts
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Source ClinicalTrials.gov