Trends of Patient-reported Outcome Measures (PROMs) in Multimorbid Medical Patients Hospitalized for an Acute Illness

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Lausanne Hospitals

About this trial

currently, PROMs and PREMs are not routinely collected and compared among medical inpatients of Swiss university hospitals, nor is a standard set of PROMs and PREMs available for use in Swiss hospitals. The project aims to examine trends in patient-reported outcomes (PROMs), including symptoms, quality of life, and distress, in multimorbid hospitalized patients from admission to 30 days post-discharge. It will also investigate whether PROMs at discharge are linked to the risk of readmission or emergency visits and explore how these outcomes differ in patients who receive low-value care. Additionally, the project will assess the relationship between patient-reported experiences (PREMs) and the provision of low-value care during the hospital stay.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

eligible for the LUCID registry (CER-VD AO_2023-00029) [Age ≥ 18 years, hospitalized in one of the five participating university hospitals (Geneva, Lausanne, Bern, Zürich, Basel), after 01.01.2014, and admitted to general internal medicine wards

Multimorbid patients (2 or more chronic diseases, defined as chronic conditions defined by international classification of diseases, 10th revision, codes with an estimated expected duration of at least 6 months or based on a clinical decision.

Acute illness

Signature of study specific informed consent

Disqualifiers

Not able to speak French, German or English

Foreseen length of stay of less than 4 days (estimated by study collaborators)

Prior inclusion in the TRADUCE study

Incapacity of discernment, i.e. cognitive impairment which could interfere with the ability to fill in PROMs tools

Trial population

Patients with 2 or more chronic diseases, hospitalized in general internal medicine divisions of all five Swiss university hospitals

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Hospitalization

    Other intervention

    The investigators collect PROMs amongst up to 1000 patients in general internal medicine divisions of all five Swiss university hospitals

Treatment groups

1,000 Participants
are divided into 1 treatment group
Group A: multimorbid patients in general internal medicine divisions of all five Swiss university hospitals1 intervention

Trial outcomes

Primary outcomes

1

Correlation of PROMS with the risk of readmission

The primary objective of the project is to explore trends in PROMs (using the Edmonton Symptom Assessment System (ESAS-r), the EQ-5D-5L index,45 and the National Comprehensive Cancer Network (NCCN) distress thermometer) of multimorbid medical hospitalized patients, from admission until 30-days post-discharge. The patients-reported outcomes will consist of patients-reported symptoms, quality of life and distress

Time frame
Day 1, Day 3, at the day of discharge (approximately day 8) and Day 30 after discharge from Hospital

Secondary outcomes

1

Correlation of PROMs at discharge and risk of hospital readmission or ED visits

assess whether PROMs ((using the Edmonton Symptom Assessment System (ESAS-r), the EQ-5D-5L index,45 and the National Comprehensive Cancer Network (NCCN) distress thermometer) at discharge are associated with the risk of hospital readmission or of emergency department visit within the next 30 days;

Time frame
Day 30 after discharge from hospital
2

Exploration of PROMs in patients who receive low-value care

explore whether PROMs ((using the Edmonton Symptom Assessment System (ESAS-r), the EQ-5D-5L index,45 and the National Comprehensive Cancer Network (NCCN) distress thermometer) trends vary in patients who do or do not receive low value care (LVC);

Time frame
Day 1, Day 3, at the day of discharge (approximately day 8) and Day 30 after discharge from Hospital
3

Explore PREMs

Explore information on Patient Reported Experiences Measures (PREMs) using a qualitative questionnaire during patients' stay at the hospital, and whether there is a correlation between the provision of LVC and qualitative analysis of PREMs

Time frame
Since 24 hours after beginning of the hospitalization up to Discharge from Hospital (approximately day 8)

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Lausanne Hospitals

Lead sponsor

Insel Gruppe AG, University Hospital Bern

Collaborator

University Hospital, Geneva

Collaborator

University Hospital, Zürich

Collaborator

University Hospital, Basel, Switzerland

Collaborator