About this trial
The investigator aims to prospectively enroll patients who were referred for transthorcic echocardiography (TTE) for the assessment of stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD). All patients underwent TTE according to established guidelines and local institutional protocols. This study will determine if TTE-based imaging evaluation can provide more informaton to improve clinical management for SCP, including fewer MACE and better decision-making of downstream investigations and therapeutic interventions.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
symptomatic patients with SCP suspected of obstructive CAD.
referred for TTE for the assessment of SCP.
≥18 years of age.
signed informed consent.
Disqualifiers
acute coronary syndromes
previous CAD or coronary revascularization
nonsinus rhythm
cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons
Trial population
Patients who were referred for TTE for the assessment of SCP suspected of CAD.
Trial design
Cohort
Prospective
Treatments tested in this trial
TTE
Diagnostic testAll patients underwent TTE according to established guidelines and local institutional protocols. The imaging data were evaluated using different image post-processing software to comprehensively analyse anatomical, functional and histological information of coronary.
Treatment groups
Trial outcomes
Primary outcomes
Major adverse cardiovascular events
Secondary outcomes
Invasive coronary angiography
Invasive coronary angiography occurred at follow-up after TTE, attributed to TTE results or unplanned.
Medication prescription
Change for medication prescription of antiplatelet agents, anti-ischemic drugs, lipid-lowering agents, angiotensin-converting enzyme inhibition and so on, attributed to TTE results or unplanned,
Coronary revascularization
PTCA, PCI or CABG occurred at follow-up after TTE, attributed to TTE results or unplanned.
Sponsors and contacts
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