TTE Improves Clinical Management of Stable Chest Pain

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorTianjin Chest Hospital

About this trial

The investigator aims to prospectively enroll patients who were referred for transthorcic echocardiography (TTE) for the assessment of stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD). All patients underwent TTE according to established guidelines and local institutional protocols. This study will determine if TTE-based imaging evaluation can provide more informaton to improve clinical management for SCP, including fewer MACE and better decision-making of downstream investigations and therapeutic interventions.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

symptomatic patients with SCP suspected of obstructive CAD.

referred for TTE for the assessment of SCP.

≥18 years of age.

signed informed consent.

Disqualifiers

acute coronary syndromes

previous CAD or coronary revascularization

nonsinus rhythm

cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons

Trial population

Patients who were referred for TTE for the assessment of SCP suspected of CAD.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • TTE

    Diagnostic test

    All patients underwent TTE according to established guidelines and local institutional protocols. The imaging data were evaluated using different image post-processing software to comprehensively analyse anatomical, functional and histological information of coronary.

Treatment groups

50,000 Participants
are divided into 1 treatment group
Group A: TTE1 intervention

Trial outcomes

Primary outcomes

1

Major adverse cardiovascular events

Time frame
10 years

Secondary outcomes

1

Invasive coronary angiography

Invasive coronary angiography occurred at follow-up after TTE, attributed to TTE results or unplanned.

Time frame
10 years
2

Medication prescription

Change for medication prescription of antiplatelet agents, anti-ischemic drugs, lipid-lowering agents, angiotensin-converting enzyme inhibition and so on, attributed to TTE results or unplanned,

Time frame
10 years
3

Coronary revascularization

PTCA, PCI or CABG occurred at follow-up after TTE, attributed to TTE results or unplanned.

Time frame
10 years

Other outcomes

Sponsors and contacts

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