Twice vs Thrice Weekly Hemodialysis: Clinical Outcomes and Quality of Life
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University
About this trial
This prospective cohort study aims to compare clinical outcomes and health-related quality of life between adults receiving established twice-weekly versus thrice-weekly maintenance hemodialysis at Assiut University Hospitals.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
- Age 18 years or older
Established end-stage kidney disease requiring maintenance hemodialysis
Receiving in-center maintenance hemodialysis at Assiut University Hospitals
On maintenance hemodialysis for at least one month before enrollment
Disqualifiers
- Acute kidney injury without established end-stage kidney disease
Hemodialysis for less than one month
Peritoneal dialysis or kidney transplantation during follow-up
Acute severe illness requiring intensive care at recruitment
Trial population
Adults with end-stage kidney disease receiving maintenance in-center hemodialysis at Assiut University Hospitals.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
130 Participants
are grouped into 2 trial groupsGroup A: Twice-weekly hemodialysis
Group B: Thrice-weekly hemodialysis
Trial outcomes
Primary outcomes
1
Health-related quality of life score
Mean total score of the Arabic Kidney Disease Quality of Life-36 (KDQOL-36) questionnaire. The KDQOL-36 score ranges from 0 to 100; higher scores indicate better health-related quality of life.
Time frame
At baseline, 3 months, and 6 monthsSecondary outcomes
1
Dialysis adequacy
Mean single-pool Kt/V (for thrice-weekly) or weekly Kt/V incorporating residual kidney clearance (for twice-weekly).
Time frame
Up to 6 months2
Residual urine output
Mean daily urine volume (mL/day) in patients with residual kidney function.
Time frame
Up to 6 months3
Hospitalization rate
Proportion of patients requiring hospital admission during follow-up.
Time frame
Up to 6 months4
Interdialytic weight gain
Mean interdialytic weight gain (kg).
Time frame
Up to 6 monthsLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: