Two Previous Cesarean and Vaginal Birth Before and After Starting Training and Protocols

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorG. d'Annunzio University

About this trial

In 2015 ObGyn Dept of Santo Spirito Hospital in Pescara (Italy) started protocol for previous CS vaginal birth. In 2021 was started a protocol for training on obstetric emergencies and protocol on two previous cesarean was endorsed. Patients attending birth in Pescara with two previous from january 2016 to December 2020, and from january 2021 to december 2025 were collected. A different counseling approach was adopted from 2021. Women's acceptance of trial of labor and maternal and fetal outcomes were collected.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

pregnant women

pregnancy above 34 weeks' gestation

cephalic presentation of the fetus

singleton and twins

Disqualifiers

pregnancy below 34 weeks' gestation

breech baby

triplets or high order multiple pregnancies

more than 2 previous CS

Trial population

pregnant women attending birth in Santo Spirito Hospital Pescara (Italy) from 01-01-2016 to 31-12-2025

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • Acceptance, rate of vaginal birth and safety

    Procedure/Surgery

    In 2021 started a new delivery protocol enhancing the opportunity of having a trial of labor in women with a history of two previous CS. Rate of acceptance, rate of successful vaginal birth, maternal and fetal outcomes were evaluated

Treatment groups

2,016 Participants
are divided into 2 treatment groups
Group A: Group 21 intervention
Group B: Group 11 intervention

Trial outcomes

Primary outcomes

1

vaginal birth after 2 cesarean

Incidence of patients having a vaginal birth after 2 CS

Time frame
5 years
2

accepted indication to trial of labor

incidence of women accepting indication to trial of labor

Time frame
5 years

Secondary outcomes

1

emergency CS

incidence of emergency CS

Time frame
5 years
2

maternal outcomes

incidence of adverse maternal outcomes (PPH, blood transfusion, vaginal tears, hysterectomy)

Time frame
5 years
3

Fetal and Neonatal adverse outcomes

Incidence of fetal/neonatal death, NICU stay, APGAR score below 7 at 5'

Time frame
5 years

Other outcomes

Sponsors and contacts

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