Primary open-angle glaucoma is a chronic optic neuropathy that often requires surgical intervention when medical treatment fails. Deep sclerectomy is a non-penetrating glaucoma surgery that aims to reduce intraocular pressure while minimizing complications. When combined with trabeculotomy, additional aqueous outflow may be achieved.
Ultrasound biomicroscopy (UBM) allows detailed imaging of the anterior segment and provides valuable information about postoperative anatomical changes that cannot be assessed clinically. This observational study aims to evaluate UBM findings after combined deep sclerectomy with trabeculotomy in patients with primary open-angle glaucoma and to correlate these findings with clinical outcomes.
Diagnosis of primary open-angle glaucoma (POAG), including juvenile open-angle glaucoma (JOAG).
Patients who underwent combined deep sclerectomy with trabeculotomy.
Clear media allowing adequate ultrasound biomicroscopy imaging.
Written informed consent obtained from the patient .
Secondary glaucomas (e.g., neovascular, uveitic, traumatic, or angle-closure glaucoma).
Previous glaucoma filtering surgery in the studied eye.
Coexisting ocular pathology affecting UBM assessment (e.g., severe corneal opacity, scleral pathology).
Patients diagnosed with primary open-angle glaucoma (POAG), including juvenile open-angle glaucoma (JOAG), who underwent combined deep sclerectomy with trabeculotomy at Minia University Hospital. All included eyes were followed postoperatively using ultrasound biomicroscopy (UBM) to evaluate intrascleral lake and filtering bleb morphology at defined follow-up intervals.
Cohort
Prospective
Ultrasound Biomicroscopy
Diagnostic testUltrasound biomicroscopy is performed as a non-invasive diagnostic imaging procedure to evaluate postoperative anterior segment anatomy, including intrascleral lake characteristics and filtering bleb morphology, in patients with primary open-angle glaucoma following combined deep sclerectomy with trabeculotomy.
Intrascleral lake area on ultrasound biomicroscopy (UBM)
Quantitative measurement of intrascleral lake area (mm²) using ultrasound biomicroscopy after combined deep sclerectomy with trabeculotomy.
Intrascleral lake height on ultrasound biomicroscopy (UBM)
Quantitative measurement of intrascleral lake height (mm) using ultrasound biomicroscopy after combined deep sclerectomy with trabeculotomy.
Filtering bleb height on ultrasound biomicroscopy (UBM)
Quantitative measurement of filtering bleb height (mm) using ultrasound biomicroscopy after combined deep sclerectomy with trabeculotomy.
Filtering bleb internal reflectivity on ultrasound biomicroscopy (UBM)
Semi-quantitative assessment of filtering bleb internal reflectivity on ultrasound biomicroscopy after combined deep sclerectomy with trabeculotomy.
Change in intraocular pressure
Change in intraocular pressure (mmHg) from baseline to 3 and 6 months after combined deep sclerectomy with trabeculotomy.
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