The main objective of the project is to demonstrate that in patients with heart failure and QRS complex of nonRBBB morphology lasting over 130 ms, UHF-ECG can differentiate patients with trueLBBB from IVCD better than existing approaches based on the assessment of QRS complex morphology and duration from 12-lead ECG.
Another goal of the proposed study is to demonstrate that trueLBBB patients will benefit more from CRT using left bundle branch pacing than from CRT using biventricular pacing.
The final aim of the project is to demonstrate that the echocardiographic and clinical response in patients with intraventricular conduction disturbance will be dependent on the degree of reduction in ventricular dyssynchrony after CRT.
HF due to ischemic or non-ischemic cardiomyopathy
known coronary angiography
NYHA II-IV
LVEF ≤40%
Age ˂18 years
heart failure from reversible causes
Moderate to severe aortic stenosis
pregnancy
Parallel
LBBAP CRT device implantation
DevicePacing system with a lead implanted in the left bundle branch area will be done.
BVP-CRT
DeviceImplantation of biventricular device
Left ventricular end-systolic volume
Left ventricular end-systolic volume reduction
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