About this trial
* Chest pain is one of the most common symptoms of heart disease. This could be due to narrowing in heart's blood vessels, which needs to be investigated. * Currently, people with a low risk of narrowing of heart vessels usually have a CT scan of the heart first. This scan is good at identifying those who do not have significant narrowing. However, the scan has some drawbacks, such as exposure to a small amount of radiation. * We are exploring if ultrasound of the neck vessels might give us similar kind of information as the CT scan. * You will be asked to attend the hospital for one visit to have an ultrasound scan of your neck. * The findings of your neck vessels will be compared with the CT scan of your heart vessels to see if there is a similarity.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age > 18 years old
Symptomatic patients with suspected CCS, judged by the clinician to require CTCA with CAC scoring, for the diagnosis of CAD
Have a RF-CL 5-15%, as calculated using ESC guidelines
Able to give informed consent to participate in the study and its follow up
Disqualifiers
Age <18 years old
Diagnosed ACS requiring hospitalization or urgent or emergent testing
Known CAD with prior MI, PCI, CABG or any angiographic evidence of CAD (≥50% lesion in a major epicardial vessel)
History of previous stroke or known peripheral vascular disease
Trial design
Single group
Treatments tested in this trial
Carotid Ultrasound
Diagnostic testCarotid ultrasound
Treatment groups
Trial outcomes
Primary outcomes
1. Reclassification of patients based on detection of carotid plaques defined as: a. Patients with no carotid plaques will reclassify as very low likelihood (<5%) b. Patients with 1-2 plaques as low likelihood for obstructive CAD (5-15%) c. Patients with
Sponsors and contacts
Click on the lead sponsor to view all of their trials.