This trial studies how well ultra-high resolution optical coherence tomography works in detecting micrometer sized early stage pancreatic cancer in participants with pancreatic cancer. Ultra-high resolution optical coherence tomography may help to accurately identify pancreatic cancer in resected pancreatic specimens.
Immediate surgery cohort: Adult patients with pancreatic cancer or IPMN
Immediate surgery cohort: Informed consent will be obtained
Adult patients undergoing pancreatic resection for a presumed IPMN
Pregnant
Single group
Optical Coherence Tomography
Procedure/SurgeryUndergo OCT
Therapeutic Conventional Surgery
Procedure/SurgeryUndergo resection will be undertaken
Laboratory Evaluation
Diagnostic testLabs will be obtained to test for cancer cell derived exosomes
Measure accuracy of using OCT to diagnose pancreatic cancer and compare with histology.
Will evaluate the accuracy of the optical coherence tomography (OCT) based diagnosis compare to the pathological diagnosis or the cancer cell derived exosomes test from the blood sample. Will compare the diagnosis results from the OCT imaging technology to standard histopathologic assessment and the blood test using 2-way tables. The agreement between two tests will be summarized with the overall agreement and the Cohen?s Kappa values.
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