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Ultrafast Ultrasound Imaging in Pediatric Cardiology

ConditionCHD - Congenital Heart Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorUniversity Hospital, Bordeaux

About this trial

About 13 in 1000 children are born with heart disease. Current tools poorly assess heart filling in children, limiting treatment. This study explores ultrafast ultrasound imaging to measure heart stiffness and perfusion in children with congenital heart disease.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with CHD

General population patients in good general health as evidenced by medical history coming to our department for a check-up OR diagnosed with small Atrial Septal Defect or small Patent Foramen Ovale

Social security affiliation

Parental or legal guardian's non-opposition

Disqualifiers

Arrhythmia

Segmental kinetic disorder.

Pacemaker or multisite stimulation, defibrillator,

Anechoic

Trial population

Every patient of CHD department of any age or any sex: 300 participants including 100 general population patients and 200 patients with CHD

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • Cardiac Ultrafast Ultrasound

    Other intervention

    Ultrafast ultrasound imaging(UFUS), ultrasound images at a very high rate, using a Verasonics system (ultrasound open platform).

Treatment groups

300 Participants
are divided into 2 treatment groups
Group A: CHD1 intervention
Group B: General population1 intervention

Trial outcomes

Primary outcomes

1

Myocardial stiffness

assessed with ultrasound data processed using the Verasonics system, to evaluate diastolic function

Time frame
Baseline
2

Myocardial perfusion

assessed with ultrasound data processed using the Verasonics system, to evaluate diastolic function

Time frame
Baseline

Secondary outcomes

1

Echocardiographic parameters

3\. Echocardiographic parameters according to international guidelines for screening for structural or functional intra-cardiac abnormalities (Lopez et al. JASE. 2024) and assessed by conventional ultrasound and ultrafast ultrasound.

Time frame
Baseline

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University Hospital, Bordeaux

Lead sponsor

Source ClinicalTrials.gov
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