Ultrasonographic Predictors of Adductor Canal Block Effectiveness in Total Knee Arthroplasty

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorKonya City Hospital

About this trial

Total knee arthroplasty (TKA) is associated with substantial postoperative pain and opioid requirements, making effective multimodal analgesia essential for early mobilization, functional recovery, and reduction of opioid-related adverse events \[1,2\]. Adductor canal block (ACB) has become a key component of enhanced recovery after surgery (ERAS) protocols because it provides effective anterior knee analgesia while largely preserving quadriceps muscle strength \[2-4\]. However, analgesic efficacy after ACB remains variable, and some patients require rescue opioid analgesia despite technically successful block placement \[5\]. Although ultrasound guidance improves block accuracy, factors such as tissue depth, anatomical variations, saphenous nerve visibility, and injectate spread pattern may influence clinical outcomes \[6,7\]. Prospective evidence regarding the predictive value of these ultrasound-derived parameters for ACB analgesic failure remains limited. Therefore, this study aims to evaluate whether preoperative ultrasound-derived tissue and target parameters-including skin-to-target depth, subcutaneous fat thickness, muscle thickness, saphenous nerve visibility, and injectate spread pattern-can predict ACB analgesic failure and early postoperative analgesic outcomes following TKA.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age ≥18 years

Scheduled for elective primary unilateral total knee arthroplasty under spinal anesthesia

American Society of Anesthesiologists (ASA) physical status I-III

Disqualifiers

Daily opioid use or chronic pain syndrome

Diabetic or other clinically diagnosed peripheral neuropathy

Coagulopathy

Infection at the injection site

Trial population

Scheduled for elective primary unilateral total knee arthroplasty under spinal anesthesia

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Adductor Canal Block (ACB) Only

    Procedure/Surgery

    The adductor canal block (ACB) will be performed in the post-anesthesia care unit (PACU) after regression of spinal anesthesia.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

ACB Failure

ACB analgesic failure will be defined as the requirement for rescue analgesia during the first 24 hours after block administration, with intravenous tramadol (1 mg/kg) administered to patients with an NRS pain score ≥4.

Time frame
0-24 hours

Secondary outcomes

1

Secondary outcome

1\. Numeric Rating Scale (NRS) Pain Scores NRS pain scores at rest and during a standardized movement (active 90° knee flexion) will be recorded at postoperative 1, 6, 12, and 24 hours.

Time frame
0-24 hour
2

Tramadol Consumption

2\. Total Tramadol Consumption Total tramadol consumption (mg) during the first 24 hours following ACB administration will be recorded.

Time frame
0-24 Hours

Other outcomes

Sponsors and contacts

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