Ultrasound-Guided Mid-Point Transverse Process to Pleura Block Versus Thoracic Paravertebral Block for Pain Management in Patients With Multiple Rib Fractures (A Prospective Randomized Double- Blinded, Non-inferiority Trial )

ConditionRib Fractures
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorAssiut University

About this trial

The aim of our study is to investigate whether the analgesic effect of MTPB is non inferior to that of TPVB in trauma patients with multiple rib fractures.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adult patients aged between 18 and 70 years, from both genders, who had uni lateral traumatic multiple rib fractures (three or more confirmed by a CT chest scan).

Disqualifiers

Significant head injury/unconsciousness (GCS less than 15).

Patients with Pain score >6.

those having significant trauma outside the chest wall, e.g., acute spine or pelvic fracture, severe traumatic brain or spinal cord injury, or abdominal visceral injuries.

Obese patients with body mass index ≥ 35.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Mid point transverse to pleura block

    Procedure/Surgery

    TPVB and MTPB was performed at a spinal level midway between the uppermost and the lowest fractured rib, with the patient in a sitting position, and under complete aseptic conditions, a linear ultrasound probe (GE Healthcare-Logiq F6) will be placed oblique parasagittally 3 cm lateral to spinous process used to identify the transverse process, pleura, superior costotransverse ligament, and the paravertebral space at the target vertebral level. After skin and subcutaneous tissue infiltration with 2-3 mL of 2% lignocaine, an 18-gauge Touhy needle was inserted under ultrasound guidance until the needle tip reaches : * the midpoint between the transverse process and the pleura (group M). * the paravertebral space (group P). A bolus dose (0.3mL/kg) of plain bupivacaine 0.5% plus 8 mg of dexamethasone was injected after negative aspiration to blood and air.

Treatment groups

70 Participants
are divided into 2 treatment groups
Group A: M (MTPB)Active comparator 1 intervention
Group B: P (TPVB)Sham comparator 1 intervention

Trial outcomes

Primary outcomes

1

The primary outcome will be the mean difference in numeric rating pain scores (NRS) between the MTPB and TPVB groups at 24-hour after the block.

Time frame
24hour

Secondary outcomes

1

• NRS scores at different times up to 24 hours.

Time frame
72hour
2

Time for first analgesic request. • Total 24 hours analgesic consumption.

Time frame
24hour
3

• Total 24 hours analgesic consumption.

Time frame
24hour
4

• Time for block performance.

Time frame
30min

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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