About this trial
This behavioral study on healthy participants aims to provide a baseline reference for assessing alterations of decision-making performance in pathological conditions. To this purpose, this single center non-interventional behavioral study will assess the extent to which decision-making performance is affected by distinct experimental manipulations, as well as by ageing effects, in 200 healthy individuals. The main questions it aims to answer are:
* to what extent is decision-making performance stable, within individuals, regardless of non-economic manipulations concerning stimuli perceptual features as well as type of processing and motor response required to participants? * are these manipulations additionally influenced by participants' age?
Healthy participants will be recruited for distinct behavioral studies assessing the effects of the aforementioned manipulations of distinct metrics of decision-making performance, such as loss aversion, risk aversion, and delay discounting.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Healthy participants, as determined by screening assessments and principal investigator judgment
The participant must be able to comply with study requirements as judged by the principal investigator
Disqualifiers
Any history of alcohol and/or drug abuse, addiction or suspicion of regular consumption of drugs of abuse
Use of any psychoactive medication, or medications known to have effect on central nervous system
Trial population
200 healty individuals, aged 18-60 years, sampled from the general population
Trial design
Cohort
Prospective
Treatments tested in this trial
No intervention
Other interventionNo intervention
Treatment groups
Trial outcomes
Primary outcomes
Individual index of loss aversion
This variable reflect the spontaneous disposition to overweigh potential losses, compared with equivalent gains in decision-making, resulting in the tendency to avoid potential losses more than approach potential gains.
Secondary outcomes
Individual index of risk aversion
This variable reflect the spontaneous preference for certain, compared with probabilistic, outcomes, resulting in the tendency to avoid risky options regardless of their expected value.
Individual index of delay discounting
This variable reflects the tendency to discount delayed utilities/rewards compared with immediate ones, resulting in choices driven by the impulsive search for immediate gains regardless of potential larger future outcomes.
Sponsors and contacts
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Istituti Clinici Scientifici Maugeri SpA
Lead sponsor
Istituto Universitario di Studi Superiori Pavia
Collaborator