Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog

ConditionsMild Cognitive Impairment Subjective Cognitive Decline

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age50+

SponsorOhio State University

About this trial

Overall, this study's primary aim is to establish a prospective, longitudinal, observational cohort study of older adults at risk for dementia from under-resourced/underrepresented communities. More specifically, older adults diagnosed with subjective cognitive decline (SCD) or Mild Cognitive Impairment (MCI) during clinical care offered via the Tele-Cog clinic would be recruited for more comprehensive data collection to characterize the clinical presentation and course of illness over multiple timepoints spread out longitudinally.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults ages 50 years and older

Diagnosed with subjective cognitive concerns (SCD) or objective cognitive decline with mostly intact functioning (MCI diagnosis) as part of clinical work up

Fluent in English

Able to provide voluntary informed consent

Disqualifiers

Diagnosis of dementia at baseline.

Inability to give informed consent.

High risk of adverse emotional or behavioral reaction based on investigator's clinical evaluation (e.g., evidence of serious personality disorder, antisocial behavior, serious current stressors, lack of meaningful social support).

Trial population

Individuals will be recruited from the Tele-Cog clinic at The Ohio State University Wexner Medical Center.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Assessments
Behavioral
Participants will undergo a standard battery of neuropsychological measures, behavioral questionnaire, and functional assessment to monitor cognition and function over time. Clinical data obtained as part of standard of care will be collected from the medical record
Neuroimaging volumetric measures
Other intervention
Neuroimaging volumetric measures will be obtained from already conducted standard of care neuroimaging.
Biofluid samples
Other intervention
Biofluid sampling data will be obtained through another protocol. All participants will be required to sign that consent to participate in this trial.

Treatment groups

1,000 Participants

are divided into 1 treatment group

Group A: Study Population3 interventions

Trial outcomes

Primary outcomes

Number of adults with Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI) at risk for dementia from under-resourced/underrepresented communities that we longitudinally collect clinical data, neuropsychology, neuroimaging, and biofluids

This study is a longitudinal collection of clinical data, neuroimaging, neuropsychological assessments, and biofluids to establish a cohort of older adults with Subjective Cognitive Decline (SCD) or Mild Cognitive Impairment (MCI) at risk for dementia from under-resourced/underrepresented communities from which hypotheses can be generated. Analysis will also include comparing the subject's longitudinal change over time data. Data will be analyzed with one way and repeated measures (ANOVAs) that will control for important covariates. All imaging data will be analyzed using qualitative visual interpretation and quantitative region of interest approach.

Time frame

5 years

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Ohio State University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: