Underwater endoscopic mucosal resection (UEMR) and endoscopic submucosal dissection (ESD) have both been reported to be two effective treatment methods for small rectal neuroendocrine tumor (NET). However, there is no consensus on the best method for the endoscopic resection of rectal NET. Therefore, we aimed to compare the efficacy and safety of UEMR and ESD for the treatment of small rectal NET.
Age from 18 to 75 years;
With a high suspicion or evidence of rectal NET assessed using EUS, CT scan or colonoscopy;
With tumor size ≤10 mm assessed by colonoscopy or EUS;
Plan to receive UEMR or ESD treatment and provide written informed consent.
Unable to tolerate ESD or UEMR as assessed by the research team;
Complicated with serious diseases such as malignant tumor, which may lead to shorter life expectancy, the research team considers that it is not suitable for inclusion in the study after comprehensive evaluation;
Rectal NET with lymph node metastasis or distant metastasis;
Received resection of rectal neuroendocrine tumor by other surgical procedures;
Nanfang Hospital, Southern Medical University
Lead sponsor
Guangdong Provincial Hospital of Traditional Chinese Medicine
Collaborator
The Eighth Affiliated Hospital of Southern Medical University
Collaborator
ZhuHai Hospital
Collaborator
Shenzhen Longgang District People's Hospital
Collaborator
Jiangmen Central Hospital
Collaborator
Yangjiang People's Hospital
Collaborator
The Third People's Hospital of Huizhou
Collaborator
the Fifth Affiliated Hospital of Zunyi Medical University (Zhuhai)
Collaborator
Ganzhou City People's Hospital
Collaborator