Urinary Proteomic Assessment of Ovarian Malignancy and Disease Progression

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorXiangya Hospital of Central South University

About this trial

The goal of this observational study is to determine the urinary proteomic characteristics in women with and without ovarian cancer. The main questions it aims to answer are:

1. What is the difference in urinary protein composition between patients with ovarian cancer and those without it? 2. Can these differences in urinary protein composition aid in the diagnosis of ovarian cancer? 3. Are urinary protein markers associated with tumor burden in urine samples from patients with ovarian cancer? 4. Can urinary protein markers be used for disease surveillance in ovarian cancer patients?

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Female patients in the gynecological ward for surgical treatment.

Initial diagnosis of "pelvic mass" or "malignant ascites" may be considered as ovarian cancer; Or the initial diagnosis of "ovarian cyst", "hydrosalpinx", "uterine fibroids" or "uterine adenomyosis" are considered as gynecological non-malignant diseases.

Over 18 years of age.

Voluntary participation and signing of informed consent.

Disqualifiers

Study participants with a prior history of malignant tumors.

Study participants with prior chronic kidney disease or renal insufficiency.

Study participants who have received or are receiving treatment for primary disease.

Study participants whose pathological diagnosis was not clear.

Trial population

primary care clinic

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

240 Participants
are grouped into 1 trial group
Group A: Diagnosis undetermined

Trial outcomes

Primary outcomes

1

Pathological diagnosis

The histological type of the disease is confirmed by surgery or biopsy

Time frame
From enrollment to the end of surgery or biopsy at 1 weeks

Secondary outcomes

1

Progression

Patients with ovarian cancer who have recurrent disease after initial treatment with serological or imaging evidence

Time frame
From enrollment to the end of treatment at 6 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.