About this trial
The multi session experimental study aims to determine dual use patterns of marijuana and tobacco by assessing the impact of price and availability of marijuana and tobacco using a cross price elasticity of demand task. The study will recruit 120 non-treatment seeking emerging young adults (18-25 years) who smoke marijuana and tobacco.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Males/females who are 18 to 25 years of age
Young adults who currently smoke commercial tobacco cigarettes (≥1x weekly in the past 30 days and for the past six months)
Young adults who currently smoke marijuana (≥4 times in past 30 days and at least weekly on average for the last six months)
Participants must report purchasing their own tobacco and marijuana at least once in the past 6 months
Disqualifiers
Intention to quit marijuana or tobacco use in the next 30 days
Self-reported illicit drug or heavy episodic alcohol use on >20 days in the past month (excluding marijuana)
Individuals who are pregnant or breastfeeding
Positive saliva test for recent THC use
Trial design
Single group
Treatments tested in this trial
Cue Reactivity
BehavioralParticipants will be exposed to neutral followed by cannabis or tobacco cues in a fixed sequence while they answer questions about their subjective state. The cues will include everyday items (e.g., eraser) and cannabis-related items (e.g., lighter).
Treatment groups
Trial outcomes
Primary outcomes
Change in self-reported cannabis craving
This study utilizes a structured cannabis cue exposure paradigm. During cue exposure, participants rate subjective craving on a scale from 0, "Not at all," to 10, "Extremely." Cannabis craving will be assessed following neutral cue exposure and then cannabis cue exposure. The primary outcome will be change in cannabis craving.
Change in self-reported tobacco craving
This study utilizes a structured tobacco cue exposure paradigm. During cue exposure, participants rate subjective craving on a scale from 0, "Not at all," to 10, "Extremely." Tobacco craving will be assessed following neutral cue exposure and then tobacco cue exposure. The primary outcome will be change in tobacco craving.
Sponsors and contacts
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Brown University
Lead sponsor
National Institutes of Health (NIH)
Collaborator
National Cancer Institute (NCI)
Collaborator