Utility of Gene Test Analysis for Diagnosis, Prognosis and Treatment of Patients With Genetic Arrhythmic Heart Disease: the ARRHYTHMIC GENE-HEART

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorUniversity Hospital of Ferrara

About this trial

The goal of this observational study is to enroll all patients evaluated at the specialized Cardiogenetic Center within the Cardiology Department of the University of Ferrara, Italy. The primary aim of the registry is to collect comprehensive clinical, genetic, and electrophysiological data from individuals with suspected or confirmed arrhythmogenic conditions. By systematically documenting patient demographics, family history, clinical presentations, diagnostic findings, and treatment outcomes, the registry seeks to enhance our understanding of the genetic basis and clinical implications of genetically driven arrhythmias and systemic syndromes. This registry will facilitate long-term follow-up of enrolled patients to assess the natural history of arrhythmogenic disorders and the effectiveness of various therapeutic interventions. Additionally, it aims to identify potential risk factors associated with adverse outcomes, such as sudden cardiac death or major arrhythmic events.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients evaluated at the Cardiogenetic Center of the University of Ferrara in Ferrara, Italy.

Having a proven cardiogenetic disease

Disqualifiers

Refuse to provide informed consents

Patients not having a cardiogenic disease

Trial population

Study Population

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

200 Participants
are grouped into 1 trial group
Group A: Patients with cardiogenetic disease

Trial outcomes

Primary outcomes

1

All-cause of death

The investigators will monitor patient's all causes death

Time frame
At one and 5 years (end of the study)
2

Cardiovascular-related death

The investigators will monitor patient's all causes death

Time frame
At one and 5 years (end of the study)

Secondary outcomes

1

Onset or worsening heart faillure

The investigators will assess patient's hemodynamic stability over the years, monitoring the onset or the worsening of heart failure

Time frame
At one and 5 years (end of the study)
2

Onset/worsening of atrial tachyarrhythmias

Time frame
At one and 5 years (end of the study)
3

Onset/worsening of ventricular tachyarrhythmias

The investigators will monitor patient's rhythm over the years, assessing the onset or the worsening of ventricular tachyarrhythmias.

Time frame
At one and 5 years (end of the study)
4

Need for PM/ICD

The investigators will evaluate procedural time of different cardiac pacing modalities

Time frame
At one and 5 years (end of the study)

Other outcomes

Sponsors and contacts

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