About this trial
In France, over 1.5 million people suffer from mild cognitive impairment, often a precursor to Alzheimer's disease (AD), whose global prevalence could reach 153 million by 2050. With no curative treatment available, maintaining patients' autonomy at home is essential to mitigate the negative effects of institutionalization and reduce economic costs. Non-pharmacological approaches, such as cognitive training, have shown potential in stabilizing cognitive functions. Research suggests that motor networks and procedural memory remain relatively preserved in early AD, and bodily engagement during encoding enhances memory. For patients with motor impairments, motor imagery (MI) activates these networks without actual movement. Additionally, dynamic visual cues, like videos, reduce cognitive load compared to static images. This project aims to combine real action, MI, and dynamic visual supports to optimize memory. By validating 120 videos of daily activities, it will assess the impact of action on recall, evaluate MI's effectiveness for patients with mobility limitations, and confirm the superiority of videos over static images. The results could support the development of digital tools, such as serious games, to enhance patients' autonomy and address aging-related challenges.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Enrollment in a social security program
Age 60 or older
French as a native language
Consent to participate
Disqualifiers
Uncorrected visual or hearing impairments
Language or motor impairments
Delirium or psychosis.
Medical treatment affecting vision, language, or motor skills (or participation in a study involving a drug or device that influences cognition).
Trial design
Crossover
Treatments tested in this trial
Control condition
BehavioralReading a sentence aloud and the participant is asked to freely recall, without delay and without cues, all the sentences presented in the block. The number of correctly recalled sentences is recorded.
Motor mental imagery
BehavioralFollowing the reading of each sentence, the participant is instructed to mentally simulate performing the action described in the sentence. And the participant is asked to freely recall, without delay and without cues, all the sentences presented in the block. The number of correctly recalled sentences is recorded.
Action execution
BehavioralAfter reading the sentence, the participant pantomimes the action described and The participant is asked to freely recall, without delay and without cues, all the sentences presented in the block. The number of correctly recalled sentences is recorded.
Treatment groups
Trial outcomes
Primary outcomes
Free recall score
The free recall score corresponds to the number of sentences spontaneously retrieved by participants after learning, measuring free retrieval ability.
Sponsors and contacts
Click on the lead sponsor to view all of their trials.