Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMayo Clinic

About this trial

This study explores the potential value of a new blood test approach for early detection of cancer.

Eligibility criteria

Qualifiers

Aim 1 Tissue

Patient has a biopsy confirmed diagnosis of target histology

Tissue samples from synchronous or metachronous primary cancers may be used as long as they are clearly of a different target organ.

Tumors from patients with an underlying genetic disorder pre-disposing to cancer may be included as long as they are stratified from those without

Disqualifiers

Aim 1 Tissue

Patient has had any transplants prior to tissue collection

Patient has received chemotherapy class drugs within 5 years prior to tissue collection

Patient has had radiation to the current target lesion prior to tissue collection

Trial design

Treatments tested in this trial

  • Non-Interventional Study

Treatment groups

6,150 Participants
are divided into 1 treatment group

Sponsors and collaborators