Validation of Drug Assays in Various Biological Matrices
ConditionInfection
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Liverpool
About this trial
This study aims to ensure that assays that measure drug concentrations are accurate and precise in different matrices when quantified using high performance liquid chromatography -tandem mass spectrometry (HPLC-MS/MS). The study involves collecting samples of various bodily fluids to quantify antimicrobials, antivirals, oral contraceptives and erectile dysfunction agents. Samples will also be obtained from individuals not receiving these medications for quality control purposes.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
> 18 years of age
Disqualifiers
Unable to give informed consent
Trial population
Healthy volunteers receiving specific medication or healthy volunteers taking no medication.
Trial design
Design model
Case-only
Time perspective
Prospective
Treatments tested in this trial
antivirals, antimicrobials, oral contraceptive, erectile dysfunction agents
Other intervention
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
To measure drug concentrations using high performance liquid chromatography -tandem mass spectrometry (HPLC-MS/MS) (accuracy and precision of assays that measure drug concentrations)
Assay validation
Time frame
Follow up up to 5 yearsSponsors and contacts
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Source ClinicalTrials.gov