Validation of the French Version of the Prediction of the Alcohol Withdrawal Severity Scale (PAWSS)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorEtablissement Public de Santé Barthélemy Durand

About this trial

The goal of this observational study is to validate the French version of the PAWSS scale in a population of patients with Alcohol Use Disorders. Prediction of Alcohol Withdrawal Severity Scale (PAWSS) has an excellent psychometric characteristics and predictive value of complicated alcohol withdrawal.

The main question it aims to answer is:

Are the psychometric properties of the French version of the PAWSS scale comparable to those of the English version in a population of alcohol use disorders subjects?

AUDs participants are included and followed for three days during their hospitalization, They will performed several scales and surveys (DSM-5 AUD criteria, AUDIT, French version of PAWSS and CIWA-AR).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Male or female, aged 18 to 60 years

Subjects with DSM-5 criteria for alcohol use disorders (AUD)

Subjects hospitalized for scheduled withdrawal or patients developing alcohol withdrawal hospitalized for another reason.

Subjects who understand French

Disqualifiers

Subjects transferred from other hospitalization services for whom a withdrawal syndrome could have already been treated.

Subjects scheduled for discharge within 48 hours.

Subjects with known uncontrolled epilepsy.

Subjects unable to understand the questionnaire.

Trial population

AUD adults subjects hospitalized

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • French version PAWSS

    Diagnostic test

    French version of the Prediction of Alcohol Withdrawal Severity Scale

Treatment groups

545 Participants
are divided into 1 treatment group
Group A: AUD participant1 intervention

Trial outcomes

Primary outcomes

1

Psychometric qualities evaluation of French PAWSS

The primary endpoint is the evaluation of the psychometric qualities of the French version of PAWSS scale (PRSAC) by measuring predictive performance through the calculation of sensitivity, specificity, and positive and negative predictive values.

Time frame
3 days

Secondary outcomes

1

The optimal cut-off score of 4 for the French version of the Prediction of the Alcohol Withdrawal Severity Scale

The optimal cut-off score of 4 will be determined by ROC curve analysis to confirm the cut-off for the French version of the Prediction of Alcohol Withdrawal Severity Scale. A French version of the Prediction of the Alcohol Withdrawal Severity Scale score of 4 or higher indicates a high risk of developing a complicated withdrawal syndrome.

Time frame
3 days
2

Reproducibility in predicting the risk of French PAWSS

Evaluate the reproducibility of the French version of the Prediction of the Alcohol Withdrawal Severity Scale in predicting the risk of complicated alcohol withdrawal syndrome by measuring inter-rater reliability through the calculation of Cohen's Kappa and Lin's concordance coefficients.

Time frame
3 days
3

Doses and Durations of Benzodiazepine

The doses and durations of benzodiazepine use during the study are collected during each participant's involvement in the study. These doses and durations will be compared between a group with a score below 4 and a group with a score of 4 or higher on the French version of the Prediction of Alcohol Withdrawal Severity Scale

Time frame
3 days

Other outcomes

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