Validation of the HAR Score for Prioritization of Patients Calling the Emergency Medical Service for Chest Pain by Emergency Call Dispatcher

ConditionChest Pain
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier le Mans

About this trial

The lifetime prevalence of chest pain in the general population is 20-40%. The etiologies to be evoked from the outset of management are those of cardiovascular origin, such as acute coronary syndrome (ACS) and pulmonary embolism. ACS is responsible for almost 20% of deaths. Delay in treatment is a major prognostic factor, given the importance of coronary reperfusion.

In France, one of the first contacts with the healthcare system is the medical regulation assistant (MRA) at the Centre 15. His or her role is to prioritize the call according to the identification of immediate signs of seriousness, and if necessary, to decide autonomously to send a rescue team before medical regulation. Depending on the reason for the call and any signs of seriousness, it prioritizes the call according to the expected response time. In line with current recommendations, all calls for chest pain should be answered by an emergency medical dispatcher (EMR) within 5 minutes. However, 60-90% of chest pain calls are not of cardiovascular origin. Their prioritization could therefore be re-qualified for longer response times.

Given the frequency of this type of call, a more efficient MRA referral strategy is needed. To achieve this, decision-support tools would be essential.

The performance of the HAR (History, Age and Risk Factors) score has been recently explored, derived from the HEART score, in a previous single-center prospective study in 2019. It stratifies the risk of a major cardiovascular event (MCE) into low (0 or 1 point), intermediate (2 or 3 points) or high (4, 5 or 6 points).

Investigator's hypothesis is that the HAR score could be entrusted to MRA, to enable them to optimize the prioritization of patients calling with non-traumatic chest pain, by qualifying low-risk chest pain calls on the one hand, which could be prioritized in P2 SNP, and high-risk calls on the other, making it possible to anticipate the dispatch of an emergency service.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patient of legal age (≥ 18 years)

Calling Center 15 from 49, 72 or 37

Expressing non-traumatic chest pain, even if this is not the main reason for seeking help.

Disqualifiers

Treatment in departments other than 49, 72 and 37

Poor understanding of the French language

Non-affiliated or non-beneficiary of a social security scheme

Person deprived of liberty by judicial or administrative decision

Trial population

Patients calling center 15 for chest pain

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

  • follow up call

    Other intervention

    A follow-up call is made to the patient 30 days (+ 5 days) after inclusion to check for the occurrence of an Major Cardio Vascular Event.

Treatment groups

796 Participants
are divided into 1 treatment group
Group A: call for chest pain1 intervention

Trial outcomes

Primary outcomes

1

Number of major cardiovascular events

Number of major cardiovascular events is measured by presence of Death from cardiological causes, Type 1 or 2 myocardial infarction, Percutaneous coronary intervention, Surgical coronary bypass surgery

Time frame
30 days

Secondary outcomes

1

Performance of the HAR Score: Sensitivity, Specificity, and Comparison Between EMR and MRA

Sensitivity, specificity, likelihood ratios of the HAR score at different decision thresholds and the area under the ROC curve, as well as reclassification rates between the evaluation of the HAR score by the EMR (Emergency Medical Dispatcher) and the MRA (Medical Regulation Assistant)

Time frame
From Day 0 to Day 30
2

Comparaison between rescue resources decided and predicted by the HAR score

The proportion of rescue resources (SMUR - VSAV...) that would have been decided according to the HAR score (≥ 4 points) compared to the proportion of rescue resources actually decided upon

Time frame
From Day 0 to Day 30
3

Time delta between the end of the MRA's score suggesting the dispatch of equipment (HAR score ≥ 4 points) and the actual decision to dispatch equipment in the current situation.

Time frame
From Day 0 to Day 30
4

Area under the ROC curve and Delong-Delong test

Time frame
From Day 0 to Day 30

Other outcomes

Sponsors and contacts

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