Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in industrialized countries and affects tens of millions of people worldwide, with a rapidly increasing prevalence. It causes irreversible central vision loss and significant difficulties in daily activities, impairing patients' quality of life and independence. Conventional clinical assessments, which focus on visual acuity and retinal imaging, do not fully reflect the functional impact of the disease.
Virtual reality (VR) makes it possible to create immersive, controlled environments to accurately measure functional vision and simulate real-life situations. The study proposes to develop a standardized and reproducible functional test in virtual reality that can complement conventional examinations and support clinical and industrial research.
Age ≥ 50 years
Sufficient knowledge of the French language
Ability to give personal, express, free, and informed consent
Ability to comply with the requirements of the protocol
Pregnant women, women in labor, or breastfeeding women
Subjects undergoing drug treatments that may cause motor, visual, vestibular, or cognitive disorders (PSA, neuroleptics, etc.) or that could interfere with the study examinations
Any concomitant intraocular condition in the eye being studied (e.g., glaucoma or cataract)
Any retinal pathology that could cause retinal atrophy other than AMD (eliminate dystrophy, chronic CRSC, pachyatrophy, resorption of vitelliform material with atrophy, high myopia, etc.)
Single group
Object recognition and selection task
Other interventionThe Sight Performance Object Task (SPOT) is a virtual reality (VR) based assessment designed to measure the object recognition and selection capabilities. It functional vision by replicating the real-world challenge of "finding things" under controlled environmental conditions.
Number of Net selection assessed by the SPOT test
Net selection is the number of selected targets, less the number of selected distractors
Number of Net selection assessed by the SPOT test
Net selection is the number of selected targets, less the number of selected distractors
Number of target selection assessed by the SPOT test
Number of target selection assessed by the SPOT test
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Streetlab
Lead sponsor
CIL - Centre Ophtalmologique d'Imagerie et de Laser
Collaborator
Fondation Ophtalmologique Adolphe de Rothschild
Collaborator
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