Validity and Reliability of the Language Memory Test (LMT) in Belgium
ConditionMultiple Sclerosis
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversitair Ziekenhuis Brussel
About this trial
This study aims to evaluate the practical and research utility of a new test assessing language and memory in people with MS. To this end, we are administering the test to a group of 100 individuals with MS who are receiving treatment at the National MS Center Melsbroek.
These data will allow us to determine whether scores on the new test correlate with those of established cognitive tests. Subsequently, we will administer the new test to 100 individuals without an MS diagnosis who are matched for age, gender, and education level. This will enable us to assess whether there are significant differences in scores between individuals with MS and those without the diagnosis.
One year later, we will re-administer the tests to the participants with MS to determine the extent to which changes in scores on the new test correspond to changes in scores on established tests.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Native Dutch speaking
Sufficient visual function (capacity to perceive test stimuli)
Minimal single hand function to execute test responses
Cognitive capacity to apprehend test instructions
Disqualifiers
Insufficient visual function (capacity to perceive test stimuli)
Inability to perform single-hand motor movements required to complete the test (e.g., tapping, selecting responses)
Insufficient cognitive capacity to understand or follow test instructions
Trial population
Adult people diagnosed with multiple sclerosis (PwMS), treated in a multidisciplinary rehabilitation program in the National Multiple Sclerosis Center (NMSC) Belgium. Healthy (no MS diagnosis) adults matched for age, gender and education
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
200 Participants
are grouped into 2 trial groupsGroup A: Adults diagnosed with multiple sclerosis
Group B: Adults without MS diagnosis
Trial outcomes
Primary outcomes
1
Language and Memory Test (LMT)
The LMT is a brief multidomain test assessing finger tapping speed, rapid lexical access, and visuospatial memory, designed for MS populations.
Time frame
Baseline, after one week and and after one yearOther outcomes
1
Symbol Digit Modalities Test (SDMT)
Participants match symbols and digits as quickly as possible following standardized oral instruc-tions. The test measures processing speed and sustained attention.
Time frame
Baseline and after one year2
Cognitive Change Scale (CCS)
The CCS assesses subjective cognitive changes over the past year and includes four validated subscales relevant to MS populations: general cognition, language and executive function, external feedback, and coping strategies.
Time frame
Baseline and after one yearLocations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Universitair Ziekenhuis Brussel
Lead sponsor
National Multiple Sclerosis Center
Collaborator
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: