Health TrialsbyHealthPanel

Validity and Reliability of the Turkish Duke Activity Status Index in Women With Lipedema

ConditionLipedema
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-65
SponsorIstanbul University - Cerrahpasa

About this trial

This study aims to evaluate the validity and reliability of the Turkish version of the Duke Activity Status Index (DASI) in women with lipedema. DASI is a 12-item questionnaire designed to assess functional capacity based on activities of daily living. The study will examine the test-retest reliability and internal consistency of the Turkish DASI and investigate its validity by examining its relationships with functional exercise capacity, lower extremity function, and health-related quality of life. The findings are expected to determine whether the Turkish DASI is a valid and reliable tool for assessing functional capacity in women with lipedema.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Female sex.

Aged 18 to <65 years.

Diagnosis of lipedema.

No participation in a physiotherapy program within the previous 3 months.

Disqualifiers

Severe visual or cognitive impairment.

Severe cardiovascular disease.

Musculoskeletal disorders or injuries affecting the lower extremities, including osteoarthritis, contracture, or osteoporosis, that may interfere with study assessments.

Skin conditions that may interfere with the assessments, such as pressure ulcers.

Trial population

The study population will consist of adult women diagnosed with lipedema who meet the predefined eligibility criteria. Participants will be recruited from individuals evaluated for lipedema and referred for physiotherapy assessment. Eligible participants who voluntarily agree to participate and provide informed consent will be enrolled in the study. The study population will be used to evaluate the validity and test-retest reliability of the Turkish version of the Duke Activity Status Index (DASI).

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Duke Activity Status Index (DASI)

    Diagnostic test

    The Duke Activity Status Index (DASI) is a 12-item self-administered questionnaire used to assess functional capacity based on activities of daily living. The total score ranges from 0 to 58.2, with higher scores indicating better functional capacity. The Turkish version of the DASI will be administered at the initial assessment and repeated after 7 days to evaluate test-retest reliability.

Treatment groups

34 Participants
are divided into 1 treatment group
Group A: Women With Lipedema1 intervention

Trial outcomes

Primary outcomes

1

Test-Retest Reliability of the Turkish Duke Activity Status Index

Test-retest reliability of the Turkish version of the Duke Activity Status Index (DASI) will be evaluated by administering the questionnaire twice, with a 7-day interval. The DASI consists of 12 items assessing functional capacity during activities of daily living, with a total score ranging from 0 to 58.2; higher scores indicate better functional capacity. Test-retest reliability will be assessed using the intraclass correlation coefficient (ICC).

Time frame
Baseline and 7 days
2

Construct Validity of the Turkish Duke Activity Status Index

Construct validity of the Turkish DASI will be evaluated by examining the relationships between DASI scores and the Six-Minute Walk Test (6MWT), Lower Extremity Functional Scale (LEFS), and 36-Item Short Form Health Survey (SF-36). Correlation analyses will be used to determine the strength and direction of the relationships between these measures.

Time frame
Baseline-7 days

Secondary outcomes

1

Functional Exercise Capacity - Six-Minute Walk Test

Functional exercise capacity will be assessed using the Six-Minute Walk Test (6MWT). Participants will be instructed to walk as far as possible along a 30-meter corridor for 6 minutes. The total distance walked will be recorded in meters, with a greater distance indicating better functional exercise capacity.

Time frame
Baseline-7 days
2

Lower Extremity Functional Status - LEFS

Lower extremity functional status will be assessed using the Lower Extremity Functional Scale (LEFS). The LEFS consists of 20 items assessing difficulty in performing daily activities. Each item is scored from 0 to 4, resulting in a total score ranging from 0 to 80. Higher scores indicate better lower extremity function.

Time frame
Baseline-7 days
3

Health-Related Quality of Life - SF-36

Health-related quality of life will be assessed using the 36-Item Short Form Health Survey (SF-36). The questionnaire evaluates eight domains of health-related quality of life. Domain scores range from 0 to 100, with higher scores indicating better health-related quality of life.

Time frame
Baseline-7 days

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Istanbul University - Cerrahpasa

Lead sponsor

Bezmialem Vakif University

Sponsor institution

Source ClinicalTrials.gov
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