Value of Biomarkers of Brain Injury for Predicting Psycho-cognitive Sequelae Secondary to Sepsis: a Prospective Multicenter Study

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorAssistance Publique - Hôpitaux de Paris

About this trial

To evaluate the value of biomarkers of neuronal and glial injury for predicting cognitive impairment (memory impairment assessed by a MoCA score \< 26/30) at 3 months in patient admitted in the intensive care unit for a sepsis or a septic shock.

Eligibility criteria

Qualifiers

Adults aged 18-80 years.

Admission to a medical or mixed ICU.

Sepsis or septic shock according to Sepsis-3 criteria.

ICU admission for less than 24 hours.

Disqualifiers

Moribund patients.

Age >80 years.

Patients under legal guardianship.

History of schizophrenia or bipolar disorder.

Trial design

Treatments tested in this trial

  • Serum

Treatment groups

No treatment groups listed

Sponsors and collaborators

Assistance Publique - Hôpitaux de Paris

Lead sponsor

URC-CIC Paris Descartes Necker Cochin

Collaborator

ANR and Ministry of Health

Collaborator