Value of Laboratory Biomarkers in Prediction of Outcome in Septic Patients

ConditionSepsis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorEgymedicalpedia

About this trial

Sepsis is defined as a dysregulated host response to infection . Despite ongoing efforts, both the incidence and mortality of sepsis have demonstrated limited reductions over the past years,There are several biomarkers that have already been studied for the early diagnosis of sepsis. Some of these markers can be used in risk prediction and monitoring the outcome of sepsis .

Some of these markers as procalcitonin and CD14, are costly and not feasible options for low- and middle-income countries . While other biomarkers are feasible and accessible to be evaluated as Triglyceride\\glucose index (TyG) , Relative Distributive Width of red blood corpuscles to albumin ratio (RAR), C-reactive protein,Neutrophile \\Lympocyte ratio and serum lactate levels .

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

patients diagnosed by hematological disease

patients refused to participate in the research

patients less than 18 years

Trial population

To evaluate the role of various laboratory biomarkers ( TyG , RAR , CAR, N\\L ratio, CRP, Serum lactate )in prediction of sepsis outcome

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • Triglyceride glucose index

    Diagnostic test

    To evaluate the role of various laboratory biomarkers ( TyG , RAR , CAR, N\\L ratio, CRP, Serum lactate )in prediction of sepsis outcome.

Treatment groups

100 Participants
are divided into 2 treatment groups
Group A: survivor group1 intervention
Group B: non-survivor group1 intervention

Trial outcomes

Primary outcomes

1

Mortality Outcome Measure

Number of Participants whom will be diagnosed with sepsis and will be admitted in the ICU

Time frame
28 days

Secondary outcomes

Other outcomes

Sponsors and contacts

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