About this trial
The goal of this observational study is to investigate the beneficial value of complementary surgery for appendiceal neuro-endocrine tumours in children.
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Eligibility criteria
This trial does not accept healthy volunteersQualifiers
All patients that were treated for an appendiceal NET before the age of 18 years old
Time period: 1990-2020
Disqualifiers
goblet cell carcinoma
adenocarcinoma
neuroendocrine carcinoma
Trial population
All patients treated for an appendiceal neuro endocrine tumour before the age of 18 during 1990 and 2020
Trial design
Cohort
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Disease free survival rate
defined as alive and free of recurrence of NET at telephone follow-up performed for this study purpose
Recurrence rate
defined as histopathologically proven metastasis/residual tumor at appendiceal stump of NET after a disease free period
Secondary outcomes
Overall survival rate
defined as alive at telephone follow-up performed for this study purpose
Complications directly related to primary and secondary treatment divided into major and minor complications according to Clavien-dindo.
Complications include, but are not limited to: * Intra-abdominal abscess, defined as a radiologically confirmed accumulation of purulent fluid in a walled-off space within the abdominal cavity. * (Adhesive) bowel obstruction requiring readmission (diagnosis based on clinical signs and symptoms such as a history of constipation, nausea, vomiting and distended abdomen) * Superficial Surgical Site Infection, as defined by the CDC criteria. (see table 1.) * Deep Surgical Site Infection, as defined by the CDC criteria.
Number of hospital readmission for complications related to treatment of NET
see title
Length of hospital stay
initial and total length of stay
Sponsors and contacts
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