Value of Right-sided Hemicolectomy for Chldren With High-risk Neuroendocrine Tumors of the Appendix

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 17
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

About this trial

The goal of this observational study is to investigate the beneficial value of complementary surgery for appendiceal neuro-endocrine tumours in children.

.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

All patients that were treated for an appendiceal NET before the age of 18 years old

Time period: 1990-2020

Disqualifiers

goblet cell carcinoma

adenocarcinoma

neuroendocrine carcinoma

Trial population

All patients treated for an appendiceal neuro endocrine tumour before the age of 18 during 1990 and 2020

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Disease free survival rate

defined as alive and free of recurrence of NET at telephone follow-up performed for this study purpose

Time frame
cross-sectional design. follow-up will be done in 2023/2024
2

Recurrence rate

defined as histopathologically proven metastasis/residual tumor at appendiceal stump of NET after a disease free period

Time frame
cross-sectional design. follow-up will be done in 2023/2024

Secondary outcomes

1

Overall survival rate

defined as alive at telephone follow-up performed for this study purpose

Time frame
cross-sectional design. follow-up will be done in 2023/2024
2

Complications directly related to primary and secondary treatment divided into major and minor complications according to Clavien-dindo.

Complications include, but are not limited to: * Intra-abdominal abscess, defined as a radiologically confirmed accumulation of purulent fluid in a walled-off space within the abdominal cavity. * (Adhesive) bowel obstruction requiring readmission (diagnosis based on clinical signs and symptoms such as a history of constipation, nausea, vomiting and distended abdomen) * Superficial Surgical Site Infection, as defined by the CDC criteria. (see table 1.) * Deep Surgical Site Infection, as defined by the CDC criteria.

Time frame
cross-sectional design. follow-up will be done in 2023/2024
3

Number of hospital readmission for complications related to treatment of NET

see title

Time frame
cross-sectional design. follow-up will be done in 2023/2024
4

Length of hospital stay

initial and total length of stay

Time frame
cross-sectional design. follow-up will be done in 2023/2024

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.