The goal of this observational study is to to analyze respiratory samples performed in mechanically ventilated ICU patients and to assess whether the SRLF criteria for defining VAP were respected among patients admited to the Intensive care medicine at a regional hospital en France
Adults ≥ 18 years
Hospitalization in Intensive care unit for the period between 01/01/2022 and 31/12/2024
Intubation and mechanical ventilation for > 48h
Positive respiratory sample
Decision of therapeutic limitation
Organ donors
Patient refuse to participate
Population includes all patients admitted to the intensive care unit for the selected period, under mechanical ventilation.
Cohort
Retrospective
Diagnostic tedst
Other intervention* Radiologic signs: 2 consecutive thorax x-ray with new onset pneumonia AND * One of the following criteria * Fever \>38,3°C without any other cause * Leucocytes \< 4000/mm3 or ≥ 12000 /mm3 * AND at least two of the following * Purulent secretions * Cough or dyspnoea * Desaturation or increase in FiO2 (+20%)
SRLF VAP criteria
Describe whether the respiratory samples obtained from ICU patients after \>48 hours of mechanical ventilation for suspected VAP met, or did not meet, the 2017 SRLF diagnostic criteria
microbial ecology in the ICU of CHSF
Prevalence of MDR in the respiratory samples
antibiotic consumption generated by VAP
To evaluate antibiotic consuming related to VAP episodes to the total antibiotic consuming in the Intensive care unit
morbidity and mortality associated with VAP
Mortality and mechanical ventilation duration among patients diagnosed of VAP
duration of antibiotic therapy for a VAP episode
Duration of antibiotherapy among patients with VAP
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