About this trial
Heart rate variability reflects the autonomic nervous system on the intrinsic activity of sinus node cells. Sympathetic hyperactivity is an adaptation to stress, while parasympathetic hyperactivity is present at rest. Thus, any variability in the heart frequency rate reflects variations in sympathetic and parasympathetic components in the autonomic nervous system. Failure to return to normal or a reduction in the variability of the heart rate in the postoperative period is correlated with complications in colorectal surgery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients operated for a scheduled colorectal resection due to cancer, diverticulitis, or Chronic Inflammatory Bowel Disease,
American Society of Anesthesiologists score 1-2
The patient must have given their free and informed consent and signed the consent form
The patient must be a member or beneficiary of a health insurance plan
Disqualifiers
Patient taking antidepressants, antipsychotics, antihypertensive beta blocker type, anti-arythmic or oral contraception
Uncontrolled diabetes or associated with a neuropathy
Arrhythmias and conduction disturbances, , coronaropathy and heart failure, kidney failure
Neuropathies
Trial population
All patients undergoing scheduled colorectal resection or operated on in the digestive surgery department of the CHU Nîmes
Trial design
Cohort
Prospective
Treatments tested in this trial
Heart Rate Variability
Diagnostic testHeart rate and RR interval Post-anonymized analysis of heart rate variability using the KUBIOS software
Treatment groups
Trial outcomes
Primary outcomes
Rate of variability of the heart rate between Day-1 to Day 7
Measured by power spectral density; ratio of the high to low frequencies
Correlation between the rate of variability of the heart rate between Day-1 to Day 7and anastomotic fistula diagnosed according to Center for Diseases Control criteria after scheduled colorectal surgery
Abdominal-pelvic imagery
Correlation between the rate of variability of the heart rate between Day-1 to Day 7 and peri-anastomotic fluid collections after scheduled colorectal surgery
Abdominal-pelvic imagery
Secondary outcomes
Correlation between the rate of variability of the heart rate between Day-1 to Day 7 and presence of intra abdominal abscess
diagnosed on CT-scan
Correlation between the rate of variability of the heart rate between Day-1 to Day 7 and presence of gut wall abscess
Correlation between the rate of variability of the heart rate between Day-1 to Day 7 and presence of pneumonia
Correlation between the rate of variability of the heart rate between Day-1 to Day 7 and presence of urinary tract infection
Sponsors and contacts
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